Protein Alignment HGTX and dlx1

DIOPT Version :10

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001093727.1
• Gene: dlx1 / 100101750
• XenbaseID: XB-GENE-876850
• Length: 251
• Species: Xenopus tropicalis
• Alignment Length: 297
• Identity: 66/297 - (22%)
• Similarity: 104/297 - (35%)
• Gaps: 127/297 - (42%)

  Fly   231 ESASPPPQGQ---NDYSPENLSSQRAKFQHHHGVNPLALHNANHAGNPGCHNNNNHMDHKLPLSF 292
            ||.|.|..|:   .::.|.|.....:...|.|
 Frog     8 ESLSSPVSGKAVFMEFGPPNQQMPPSPMSHGH--------------------------------- 39

  Fly   293 LGPPLAALHSMTTEMKGQGVGGSSAS-ANGLSYSHSPNSHLISDRGSGGSSSSSSTTTTNTNSQG 356
                 .::|.:.::......|.||.| |.|..|.:|.:||
 Frog    40 -----YSMHCLHSQHDSSYSGASSFSRALGYPYVNSVSSH------------------------- 74

  Fly   357 APNPHGIDTILSKPPPVTSAGLSALTGAGIPRFSIAAAAAGMAQYLSQSQGAPLKTHAGHIVDRT 421
            :.||: |.|:.|.|   .|:.||                                        :|
 Frog    75 SSNPY-ISTVQSYP---NSSSLS----------------------------------------QT 95

  Fly   422 HLYWPGLQGLVANPIAWRERLSNTMSANLSQSHQHHPSNDKDGKKKHTRPTFSGQQIFALEKTFE 486
            .|..||               :.|..:.:.:..:.. .|.|..|.:..|..:|..|:.||.:.|:
 Frog    96 RLEEPG---------------AETEKSTVVEGGEVR-FNGKGKKIRKPRTIYSSLQLQALNRRFQ 144

  Fly   487 QTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRK 523
            ||:|||.||||:||.:||::::|||:||||:|:|::|
 Frog   145 QTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKK 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	29/160 (18%)
		Homeodomain	465..523	CDD:459649	29/57 (51%)
dlx1	NP_001093727.1	Homeodomain	125..181	CDD:459649	28/55 (51%)