DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HGTX and emx2

DIOPT Version :9

Sequence 1:	NP_001368954.1	Gene:	HGTX / 53446	FlyBaseID:	FBgn0040318	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001128284.1	Gene:	emx2 / 100038069	XenbaseID:	XB-GENE-481028	Length:	247	Species:	Xenopus tropicalis

Alignment Length:	198	Identity:	51/198 - (25%)
Similarity:	80/198 - (40%)	Gaps:	73/198 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   402 LSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVANP-IAWRERLS---------------NTMSAN- 449
            ||.:..||:......       :.|..:|:.:|| :.:.|.:|               :.::|:
Frog    36 LSYANSAPMNPFLNG-------FHPTGRGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHP 93

  Fly   450 LSQSHQHHP----------------------------SNDKDG-----------KKKHTRPTFSG 475
            |..||..||                            .||...           |.|..|..||.
Frog    94 LPTSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDTSAESFLLHNALARKPKRIRTAFSP 158

  Fly   476 QQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRHAAEMATAKRKQDDMG 540
            .|:..||..||:..|:.|.||.:||::|.::|:||||||||||||::          ::|.::.|
Frog   159 SQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFK----------RQKLEEEG 213

  Fly   541 GDN 543
            .|:
Frog   214 SDS 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709
HGTX	NP_001368954.1	Homeobox	469..523	CDD:395001	28/53 (53%)
emx2	NP_001128284.1	Homeobox	153..206	CDD:365835	28/62 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000