DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SC35 and NSR1

DIOPT Version :9

Sequence 1:	NP_001188794.1	Gene:	SC35 / 53444	FlyBaseID:	FBgn0265298	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_011675.1	Gene:	NSR1 / 853064	SGDID:	S000003391	Length:	414	Species:	Saccharomyces cerevisiae

Alignment Length:	179	Identity:	49/179 - (27%)
Similarity:	73/179 - (40%)	Gaps:	53/179 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SLKVDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYTRESRGFAFVRFYDKRDAEDALEAMDGRM 88
            :|.:.||::....:.:..:|.:.|||..:.||....|.:.:||.:|:|.:..||:.||:|:.|..
Yeast   268 TLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKALDALQGEY 332

  Fly    89 LDGRELRVQMARYGRPSSPTRSSSGRRG-----GGGGGGSGGRRRSRSRSPMRRRSRSPRRRSYS 148
            :|.|.:|:..      |||..::.|.||     ||.|||.||.|....
Yeast   333 IDNRPVRLDF------SSPRPNNDGGRGGSRGFGGRGGGRGGNRGFGG----------------- 374

  Fly   149 RSRSPGSHSPERRSKFSRSPVRGDSRNGIG----SGSGGLAPAASRSRS 193
                                 ||.:|.|.|    ||||.......|||:
Yeast   375 ---------------------RGGARGGRGGFRPSGSGANTAPLGRSRN 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SC35	NP_001188794.1	RRM	<24..>100	CDD:223796	23/75 (31%)
SC35	NP_001188794.1	RRM_SRSF2_SRSF8	25..97	CDD:240757	23/71 (32%)
NSR1	NP_011675.1	RRM1_gar2	169..244	CDD:409881
NSR1	NP_011675.1	RRM2_gar2	269..341	CDD:409882	23/71 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.928771	Normalized mean entropy	S1239
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860