Protein Alignment SC35 and TRA2B

DIOPT Version :10

• Sequence 1: NP_652612.1
• Gene: SC35 / 53444
• FlyBaseID: FBgn0265298
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_004584.1
• Gene: TRA2B / 6434
• HGNCID: 10781
• Length: 288
• Species: Homo sapiens
• Alignment Length: 181
• Identity: 71/181 - (39%)
• Similarity: 88/181 - (48%)
• Gaps: 38/181 - (20%)

  Fly    13 ARPPPRIDGMVSLKVDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYTRESRGFAFVRFYDKRDA 77
            |.|.|.    ..|.|..|:..||..|||.||.:.|.:.|:.|..|:.:|.|||||||.|.:..||
Human   112 ANPDPN----CCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDA 172

  Fly    78 EDALEAMDGRMLDGRELRVQMARYGRPSS---------PTRSSSGRRG----------------- 116
            ::|.|..:|..||||.:||..:...||.:         ||..||.||.
Human   173 KEAKERANGMELDGRRIRVDFSITKRPHTPTPGIYMGRPTYGSSRRRDYYDRGYDRGYDDRDYYS 237

  Fly   117 ---GGGGGGSGGRRRSRSRSPM-RRRSRSP--RRRSY-SRSRSPGSHSPER 160
               .|||||.||.|.::.|..: ||||.||  .|..| ||||| .|:||.|
Human   238 RSYRGGGGGGGGWRAAQDRDQIYRRRSPSPYYSRGGYRSRSRS-RSYSPRR 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SC35	NP_652612.1	RRM_SRSF2_SRSF8	25..97	CDD:409751	33/71 (46%)
TRA2B	NP_004584.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..114		1/1 (100%)
		RRM_TRA2	117..196	CDD:409798	34/82 (41%)
		Linker	193..230		8/36 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	196..225		8/28 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..288		26/47 (55%)