Protein Alignment SC35 and SRSF3

DIOPT Version :9

• Sequence 1: NP_001188794.1
• Gene: SC35 / 53444
• FlyBaseID: FBgn0265298
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_003008.1
• Gene: SRSF3 / 6428
• HGNCID: 10785
• Length: 164
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 67/191 - (35%)
• Similarity: 82/191 - (42%)
• Gaps: 66/191 - (34%)

  Fly    27 VDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYTRESRGFAFVRFYDKRDAEDALEAMDGRMLDG 91
            |.||.......:|.|.|...|.:..:::     .|...|||||.|.|.|||.||:..:|||.|.|
Human    14 VGNLGNNGNKTELERAFGYYGPLRSVWV-----ARNPPGFAFVEFEDPRDAADAVRELDGRTLCG 73

  Fly    92 RELRVQMARYGRPSSPTRSSSGRRGGGGGGGSGGRRRSRSRSP-----------MRRRS-----R 140
            ..:||::                        |.|.:|||:|.|           .||||     |
Human    74 CRVRVEL------------------------SNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRR 114

  Fly   141 SPRRRSYSRSRSPGSHSPERRSKFSRS------PVRGDSRNGIGSGSGGLAPAASRSRSRS 195
            ||||||:||||| .|.|.:||.:.|.|      |.|..||              |||||||
Human   115 SPRRRSFSRSRS-RSLSRDRRRERSLSRERNHKPSRSFSR--------------SRSRSRS 160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SC35	NP_001188794.1	RRM	<24..>100	CDD:223796	27/72 (38%)
		RRM_SRSF2_SRSF8	25..97	CDD:240757	26/69 (38%)
SRSF3	NP_003008.1	Sufficient for interaction with NXF1	1..90		32/104 (31%)
		RRM_SRSF3	6..86	CDD:241089	29/100 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	81..164		40/95 (42%)
		2 X approximate repeats, basic	119..164		24/57 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1533297at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920