DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SC35 and srsf10

DIOPT Version :9

Sequence 1:	NP_001188794.1	Gene:	SC35 / 53444	FlyBaseID:	FBgn0265298	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_001011096.1	Gene:	srsf10 / 496509	XenbaseID:	XB-GENE-492982	Length:	258	Species:	Xenopus tropicalis

Alignment Length:	216	Identity:	83/216 - (38%)
Similarity:	107/216 - (49%)	Gaps:	42/216 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RPPPRIDGMVSLKVDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYTRESRGFAFVRFYDKRDAE 78
            |||     ..||.|.|:......|||||.|.|.|.:.|:|:|.|.|||..||||:|:|.|.||||
Frog     6 RPP-----NTSLFVRNIADDIRSEDLRREFGRYGPIVDVYVPLDYYTRRPRGFAYVQFEDVRDAE 65

  Fly    79 DALEAMDGRMLDGRELRVQMARYGRPS-SPTRSSSGRRGGGGGGGSGGR--RRSRSRSPMRRRSR 140
            |||..:|.:.:.||::.:|.|:..|.: :..::..||...|.......|  |||||||..|||||
Frog    66 DALHNLDKKWICGRQIEIQFAQGDRKTPNQMKAKEGRSTYGSSRYDDDRHNRRSRSRSYERRRSR 130

  Fly   141 ------------SPR--------------------RRSYSRSRSPGSHSPERRSKFSRSPVRGDS 173
                        |||                    |.:.||||| ||:|..|.....:..|| :.
Frog   131 SRSFEQNYGRSYSPRGRGGERLHRSRSRSDHGRFNRHNRSRSRS-GSNSRSRSKSEPKKTVR-EQ 193

  Fly   174 RNGIGSGSGGLAPAASRSRSR 194
            |:|..|.|.|.:.|.|:||.|
Frog   194 RSGSRSHSRGHSKADSKSRCR 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SC35	NP_001188794.1	RRM	<24..>100	CDD:223796	37/75 (49%)
SC35	NP_001188794.1	RRM_SRSF2_SRSF8	25..97	CDD:240757	35/71 (49%)
srsf10	NP_001011096.1	RRM_SF	10..93	CDD:388407	39/82 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1533297at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920