Protein Alignment SC35 and RBMXL2

DIOPT Version :10

• Sequence 1: NP_652612.1
• Gene: SC35 / 53444
• FlyBaseID: FBgn0265298
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_055284.3
• Gene: RBMXL2 / 27288
• HGNCID: 17886
• Length: 392
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 69/227 - (30%)
• Similarity: 89/227 - (39%)
• Gaps: 66/227 - (29%)

  Fly    25 LKVDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYTRESRGFAFVRFYDKRDAEDALEAMDGRML 89
            |.:..|...|..:.|...|.:.|.:.::.:.:||.|.:|||||||.|....||:.|...|:|:.|
Human    10 LFIGGLNLETDEKALEAEFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKAAARDMNGKSL 74

  Fly    90 DGRELRVQMA--------RYGRPSSPTRSSS------GRRGGGGG-------GG---SGG----- 125
            ||:.::|..|        |.|.|  |.||..      |.||||||       ||   .||
Human    75 DGKAIKVAQATKPAFESSRRGPP--PPRSRGRPRFLRGTRGGGGGPRRSPSRGGPDDDGGYTADF 137

  Fly   126 -RRRSRSRSPM------RRRSRSPRRRSYS----------RSRS------PGSHSPERRSKF--S 165
             .|.||:..||      ||....|:|.:.|          |.|:      .|...|.||...  .
Human   138 DLRPSRAPMPMKRGPPPRRVGPPPKRAAPSGPARSSGGGMRGRALAVRGRDGYSGPPRREPLPPR 202

  Fly   166 RSPVRGDSRNGIGSGSG----------GLAPA 187
            |.|..|....|..|..|          |.||:
Human   203 RDPYLGPRDEGYSSRDGYSSRDYREPRGFAPS 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SC35	NP_652612.1	RRM_SRSF2_SRSF8	25..97	CDD:409751	25/71 (35%)
RBMXL2	NP_055284.3	RRM_RBMX_like	7..86	CDD:409816	27/75 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	67..392		49/170 (29%)
		RBM1CTR	173..217	CDD:400429	10/43 (23%)