DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SC35 and 4930595M18Rik

DIOPT Version :9

Sequence 1:	NP_001188794.1	Gene:	SC35 / 53444	FlyBaseID:	FBgn0265298	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_775611.2	Gene:	4930595M18Rik / 245492	MGIID:	3045300	Length:	829	Species:	Mus musculus

Alignment Length:	179	Identity:	61/179 - (34%)
Similarity:	87/179 - (48%)	Gaps:	39/179 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 IDGMVSLKVDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYTRESRGFAFVRFYDKRDAEDALEA 83
            :|||..|||:||.:.|:...|:.|||..|.:||:||||:..|.|..||||:.||:|.||.|||.:
Mouse    10 VDGMTCLKVENLAHHTSSYTLKHVFEDYGPLGDVYIPRNHLTEEHYGFAFIHFYNKCDANDALHS 74

  Fly    84 MDGRMLDGRELRVQMA-----RYGRPSSPTRSSSGR---------------------------RG 116
            ::|.:|||.:|:|||.     .|.:|.    .||||                           |.
Mouse    75 LNGFLLDGCKLKVQMVYNDDPHYAQPD----CSSGRQYQYKEENHDLQSECERQHFSNTRIQTRS 135

  Fly   117 GGGGGGSGGRRRSRSRSPMRRRSRSPR---RRSYSRSRSPGSHSPERRS 162
            .....|.....:|:|.:.:.|||.|.|   :.|.|..:.|....|:.::
Mouse   136 HSRSSGDDSEFKSQSSNHLHRRSSSTRFKTQSSVSTQQLPNRACPKSKN 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SC35	NP_001188794.1	RRM	<24..>100	CDD:223796	39/80 (49%)
SC35	NP_001188794.1	RRM_SRSF2_SRSF8	25..97	CDD:240757	36/71 (51%)
4930595M18Rik	NP_775611.2	RRM	<14..176	CDD:223796	56/165 (34%)
		RRM_SF	16..88	CDD:302621	36/71 (51%)
		zf-RING_2	775..816	CDD:290367
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4207
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23147
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870