Protein Alignment SC35 and SRSF8

DIOPT Version :9

• Sequence 1: NP_001188794.1
• Gene: SC35 / 53444
• FlyBaseID: FBgn0265298
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_115285.1
• Gene: SRSF8 / 10929
• HGNCID: 16988
• Length: 282
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 119/214 - (55%)
• Similarity: 141/214 - (65%)
• Gaps: 30/214 - (14%)

  Fly    10 LGAARPPPRIDGMVSLKVDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYTRESRGFAFVRFYDK 74
            :...||||.:|||::||||||||||:|:.||||||:.|.|||:||||:.:|:..||||||||:|:
Human     1 MSCGRPPPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDR 65

  Fly    75 RDAEDALEAMDGRMLDGRELRVQMARYGRPSSPTRSSSGR-RGGGGGGGSGGRRRS---RSRSPM 135
            |||:||..||||..|||||||||:|||||...| ||..|. ||...|||.|.|.||   |||||.
Human    66 RDAQDAEAAMDGAELDGRELRVQVARYGRRDLP-RSRQGEPRGRSRGGGYGRRSRSYGRRSRSPR 129

  Fly   136 RR---RSRSP---RRRSYSR------SRSPGSHSPERRSKFSRSPVR----GDSRNGIGS--GSG 182
            ||   |||.|   |.||.||      ||||.|.||..||::||||..    .:||.| ||  .|.
Human   130 RRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYG-GSHYSSS 193

  Fly   183 GLAPA------ASRSRSRS 195
            |.:.:      :|||.|:|
Human   194 GYSNSRYSRYHSSRSHSKS 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SC35	NP_001188794.1	RRM	<24..>100	CDD:223796	53/75 (71%)
		RRM_SRSF2_SRSF8	25..97	CDD:240757	51/71 (72%)
SRSF8	NP_115285.1	RRM_SRSF2_SRSF8	16..88	CDD:409751	51/71 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..282		58/124 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152425
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4207
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3715
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003650
OrthoInspector	1	1.000	-	-		otm40641
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23147
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3014
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.890