Protein Alignment SF2 and SRSF9

DIOPT Version :9

• Sequence 1: NP_001247139.1
• Gene: SF2 / 53443
• FlyBaseID: FBgn0283477
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_003760.1
• Gene: SRSF9 / 8683
• HGNCID: 10791
• Length: 221
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 130/244 - (53%)
• Similarity: 160/244 - (65%)
• Gaps: 36/244 - (14%)

  Fly     2 GSRNECRIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRRG-PPFAFVEFEDARDADDAVKARD 65
            |...:.||||||||.|:|.||::|||:|:|::..::||||.| .|||||.|||.|||:||:..|:
Human     9 GGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRN 73

  Fly    66 GYDYDGYRLRVEFPRG-GGPGSYRGGNRNDRSRDGGGRMGGRGPPAKRSQYRVMVTGLPASGSWQ 129
            ||||...||||||||. ||.|.:..|.||             |||.:||.:||:|:|||.|||||
Human    74 GYDYGQCRLRVEFPRTYGGRGGWPRGGRN-------------GPPTRRSDFRVLVSGLPPSGSWQ 125

  Fly   130 DLKDHMREAGDVCFADTYKDGSGVVEFLRHEDMKYAIKKLDDSRFRSHEGEVAYIRVREDSGDND 194
            |||||||||||||:||..|||.|:||:||.|||:||::||||::|||||||.:||||..     :
Human   126 DLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYIRVYP-----E 185

  Fly   195 RGGGGGGSGGGGGGSGGGGSRDYRDRSRSRSFSSRPRRRGTPTY-SPVR 242
            |....|.|               |.||.||...|..:.||:|.| ||.|
Human   186 RSTSYGYS---------------RSRSGSRGRDSPYQSRGSPHYFSPFR 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	46/77 (60%)
		RRM2_SRSF1_like	115..188	CDD:410013	54/72 (75%)
SRSF9	NP_003760.1	RRM1_SRSF9	15..86	CDD:241042	44/70 (63%)
		RRM2_SRSF9	104..186	CDD:410161	58/86 (67%)
		Interaction with SAFB1	188..200		5/26 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..221		15/46 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	109	1.000	Domainoid score	I6370
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D523875at33208
OrthoFinder	1	1.000	-	-		FOG0000217
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102665
Panther	1	1.100	-	-	O	PTHR23147
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1390
SonicParanoid	1	1.000	-	-		X1030
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.810