DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SF2 and PIN4

DIOPT Version :9

Sequence 1:	NP_001247139.1	Gene:	SF2 / 53443	FlyBaseID:	FBgn0283477	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_009502.1	Gene:	PIN4 / 852229	SGDID:	S000000147	Length:	668	Species:	Saccharomyces cerevisiae

Alignment Length:	149	Identity:	27/149 - (18%)
Similarity:	53/149 - (35%)	Gaps:	42/149 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IYVGNLPPDIRTKDIQDLF------------HKFGKVTFVDLKNRRGPPFAFVEFEDARDADDAV 61
            |.:.|:|..|:.:.:.|:.            :.|....|      ||  .||..|....:....:
Yeast    87 IVIKNIPFAIKKEQLLDIIEEMDLPLPYAFNYHFDNGIF------RG--LAFANFTTPEETTQVI 143

  Fly    62 KARDGYDYDGYRLRVEF------------------PRGGGPGSYRGGNRNDRSRDGGGRMGGRG- 107
            .:.:|.:..|.:|:||:                  .||.....:|  :.::.|.|...:|.|.|
Yeast   144 TSLNGKEISGRKLKVEYKKMLPQAERERIEREKREKRGQLEEQHR--SSSNLSLDSLSKMSGSGN 206

  Fly   108 -PPAKRSQYRVMVTGLPAS 125
             ..:....:..::.|:.|:
Yeast   207 NNTSNNQLFSTLMNGINAN 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	17/100 (17%)
SF2	NP_001247139.1	RRM2_SRSF1_like	115..188	CDD:410013	2/11 (18%)
PIN4	NP_009502.1	RRM_PIN4_like	84..162	CDD:240699	17/82 (21%)
PIN4	NP_009502.1	R3H_RRM	305..367	CDD:100068
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900