Protein Alignment SF2 and Srsf1

DIOPT Version :10

• Sequence 1: NP_652611.1
• Gene: SF2 / 53443
• FlyBaseID: FBgn0283477
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_001103022.1
• Gene: Srsf1 / 689890
• RGDID: 1587490
• Length: 248
• Species: Rattus norvegicus
• Alignment Length: 252
• Identity: 159/252 - (63%)
• Similarity: 185/252 - (73%)
• Gaps: 20/252 - (7%)

  Fly     5 NECRIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRR-GPPFAFVEFEDARDADDAVKARDGYD 68
            |:|||||||||||||||||:|:|:|:|.:..:|||||| |||||||||||.|||:|||..|||||
  Rat    14 NDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYD 78

  Fly    69 YDGYRLRVEFPRGGGPGSYRGGNRNDRSRDGGGRMGGR-GPPAKRSQYRVMVTGLPASGSWQDLK 132
            ||||||||||||.|     ||..|......|||...|| |||::||:.||:|:|||.||||||||
  Rat    79 YDGYRLRVEFPRSG-----RGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLK 138

  Fly   133 DHMREAGDVCFADTYKDGSGVVEFLRHEDMKYAIKKLDDSRFRSHEGEVAYIRVREDSGDNDRGG 197
            ||||||||||:||.|:||:|||||:|.|||.||::|||:::|||||||.|||||:.|       |
  Rat   139 DHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVD-------G 196

  Fly   198 GGGGSGGGGGGSGGGGSRDYRDRSRSRSFSSRPRR-RGTPTYSPVRRQSYSRSRSRS 253
            ....|.|.........||. |.||.|||.|..||| ||:|.|||    .:||||||:
  Rat   197 PRSPSYGRSRSRSRSRSRS-RSRSNSRSRSYSPRRSRGSPRYSP----RHSRSRSRT 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_652611.1	RRM_SF	3..80	CDD:473069	60/75 (80%)
		RRM2_SRSF1_like	115..188	CDD:410013	55/72 (76%)
Srsf1	NP_001103022.1	RRM1_SRSF1	12..90	CDD:410010	60/75 (80%)
		RRM2_SRSF1	113..196	CDD:410160	61/89 (69%)