Protein Alignment SF2 and SRSF5

DIOPT Version :9

• Sequence 1: NP_001247139.1
• Gene: SF2 / 53443
• FlyBaseID: FBgn0283477
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_001034554.1
• Gene: SRSF5 / 6430
• HGNCID: 10787
• Length: 272
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 99/252 - (39%)
• Similarity: 131/252 - (51%)
• Gaps: 33/252 - (13%)

  Fly     7 CRIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRRGPPFAFVEFEDARDADDAVKARDGYDYDG 71
            ||:::|.|.|..|.||::..|..:|::..:|||  ||  |.||||||.|||||||...||.:...
Human     4 CRVFIGRLNPAAREKDVERFFKGYGRIRDIDLK--RG--FGFVEFEDPRDADDAVYELDGKELCS 64

  Fly    72 YRLRVEFPRGGGPGSYRGGNRNDRSRDGGGRMGGRGPPAKRSQYRVMVTGLPASGSWQDLKDHMR 136
            .|:.:|..|....|....|..:||......|...|..|..|::.|::|..|.:..|||||||.||
Human    65 ERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMR 129

  Fly   137 EAGDVCFADTY--KDGSGVVEFLRHEDMKYAIKKLDDSRFRSHEGEVAYIRVREDSGDNDRGGGG 199
            :||:|.|||.:  |...|||||..:.|:|.||:||........:     |::.|.|..:.|
Human   130 QAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRK-----IKLIEGSKRHSR---- 185

  Fly   200 GGSGGGGGGSGGGGSRDYRDRSRSRSFS---SRPRRRGTPTYSPVRRQSYSRSRSRS 253
                          ||. |.|||:||.|   ||.|.|...:||..|.:|.|||||:|
Human   186 --------------SRS-RSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKS 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	33/72 (46%)
		RRM2_SRSF1_like	115..188	CDD:410013	31/74 (42%)
SRSF5	NP_001034554.1	RRM1_SRSF5	5..74	CDD:410008	32/72 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..105		8/31 (26%)
		RRM2_SRSF5	99..179	CDD:410158	34/84 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..272		27/73 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000217
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1390
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940