DRSC/TRiP Functional Genomics Resources

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Protein Alignment SF2 and RBM28

DIOPT Version :10

Sequence 1:NP_652611.1 Gene:SF2 / 53443 FlyBaseID:FBgn0283477 Length:255 Species:Drosophila melanogaster
Sequence 2:NP_060547.2 Gene:RBM28 / 55131 HGNCID:21863 Length:759 Species:Homo sapiens


Alignment Length:188 Identity:38/188 - (20%)
Similarity:78/188 - (41%) Gaps:19/188 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 IYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRRGPP----FAFVEFEDARDADDAVKARDGYDY 69
            ::||.|||..|::.:::||.:.|.|....:...:|..    |.:|.|....|...|:|  :...:
Human     6 LFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALK--EITTF 68

  Fly    70 DGYRLRVEFPRGGGPGSYRGGNRNDRSRDGGGRMGGRGPPAKRSQY-----RVMVTGLPASGSWQ 129
            :|.::.|...:.......:...:|:.|     ....:.|.||:::.     |:::..|....|..
Human    69 EGCKINVTVAKKKLRNKTKEKGKNENS-----ECPKKEPKAKKAKVADKKARLIIRNLSFKCSED 128

  Fly   130 DLKDHMREAGDVCFADTYKDGSGVVE---FLRHEDMKYAIKKLDDSRFRSHEGEVAYI 184
            |||....:.|.|...:..:...|.:.   |::.:::..|.|.|.....:..:|....:
Human   129 DLKTVFAQFGAVLEVNIPRKPDGKMRGFGFVQFKNLLEAGKALKGMNMKEIKGRTVAV 186

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SF2NP_652611.1 RRM_SF 3..80 CDD:473069 19/74 (26%)
RRM2_SRSF1_like 115..188 CDD:410013 14/78 (18%)
RBM28NP_060547.2 RRM1_RBM28_like 5..81 CDD:409847 19/76 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 84..105 3/25 (12%)
RRM2_RBM28_like 115..190 CDD:409848 14/72 (19%)
PABP-1234 126..721 CDD:130689 12/61 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 201..330
RRM3_RBM28_like 335..417 CDD:409849
RRM4_RBM28_like 487..581 CDD:409850
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 594..759
Blue background indicates that the domain is not in the aligned region.

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