DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SF2 and snrnp70

DIOPT Version :9

Sequence 1:	NP_001247139.1	Gene:	SF2 / 53443	FlyBaseID:	FBgn0283477	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001003875.1	Gene:	snrnp70 / 445398	ZFINID:	ZDB-GENE-040825-2	Length:	495	Species:	Danio rerio

Alignment Length:	265	Identity:	74/265 - (27%)
Similarity:	97/265 - (36%)	Gaps:	87/265 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IYVGNLPPDIRTKDIQDLFHKFG--KVTFVDLKNRRGPP--FAFVEFEDARDADDAVKARDGYDY 69
            ::|..:..|.....::..|..:|  |..::....:.|.|  :||:|:|..||...|.|..||...
Zfish   105 LFVARINYDTTESKLRREFEVYGPIKRIYIVYNKKTGKPRGYAFIEYEHERDMHSAYKHADGKKI 169

  Fly    70 DGYRLRVEFPR------------GGG-PGSYRGG--------NRNDRSR-----DGGGRMGGRGP 108
            ||.|:.|:..|            ||| .|:.|||        .|:|.||     .|..|...||.
Zfish   170 DGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIKHSGRDDTSRYDDRPIGSDRDRDRGE 234

  Fly   109 PAKRSQYRVMVTGLPASGSWQDLKDHMREAGDVCFADTYKDGSGVVEFLRHEDMKYAIKKLDDSR 173
            ..:||:.|                |..:|.|:       :..|...|..||.
Zfish   235 RRERSRER----------------DRDKERGE-------RRRSRSRERRRHT------------- 263

  Fly   174 FRSHEGEVAYIRVREDSGDNDRGGGGGGS---------GGGGGGSGGGGSRDY-RDRSRSRSFSS 228
             ||||      |.|..:||.    .||.|         ||.|.|.....|||. |||.|.|...|
Zfish   264 -RSHE------RERAAAGDE----AGGSSRRRERERERGGAGAGESRERSRDRDRDRDRKRRSRS 317

  Fly   229 RPRRR 233
            |.|:|
Zfish   318 RDRKR 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	21/74 (28%)
SF2	NP_001247139.1	RRM2_SRSF1_like	115..188	CDD:410013	13/72 (18%)
snrnp70	NP_001003875.1	U1snRNP70_N	2..>57	CDD:289024
		RRM	<98..>182	CDD:223796	22/76 (29%)
		RRM_snRNP70	102..187	CDD:240682	22/81 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900