DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SF2 and srsf6

DIOPT Version :9

Sequence 1:	NP_001247139.1	Gene:	SF2 / 53443	FlyBaseID:	FBgn0283477	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001001248.1	Gene:	srsf6 / 407954	XenbaseID:	XB-GENE-488901	Length:	568	Species:	Xenopus tropicalis

Alignment Length:	274	Identity:	112/274 - (40%)
Similarity:	143/274 - (52%)	Gaps:	47/274 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRRGPPFAFVEFEDARDADDAVKARDGYDYDGY 72
            |:|:|.|...:|.||||..|..:||:..|||||..|    ||||||:|||||||...:|.|..|.
Frog     3 RVYIGRLGYHVREKDIQRFFGGYGKLLEVDLKNGYG----FVEFEDSRDADDAVYELNGKDLCGE 63

  Fly    73 RLRVEFPRGG-------GPGSYRGGNRNDRSRDGGGRMGGR---GPPAKRSQYRVMVTGLPASGS 127
            |:.||..||.       |.|| |.|.||.||        ||   |||. |:::|::|..|.:..|
Frog    64 RVIVEHARGPRRDRDGYGYGS-RSGYRNQRS--------GRDKYGPPV-RTEFRLIVENLSSRCS 118

  Fly   128 WQDLKDHMREAGDVCFADTYKD--GSGVVEFLRHEDMKYAIKKLDDSRFRSHEGEVAYIRVREDS 190
            ||||||.||:||:|.:||.:|:  ..||:||..:.|||.|::|||.:......     ||:.|..
Frog   119 WQDLKDFMRQAGEVTYADAHKERANEGVIEFRSYSDMKRAMEKLDGTEINGRR-----IRLVEGK 178

  Fly   191 GDNDRGGGGGGSGGGGGGSGGGGSRDYR-DRSRSRSFSSRPRRRG----------TPT-----YS 239
            ..:.|...|..|...........||..: ..|||||.|..|.::|          :||     .|
Frog   179 ARHRRSYSGSRSRSRSRSRRRSRSRSRQPSHSRSRSRSHSPAKKGRSPAKKSRSHSPTKSSHSQS 243

  Fly   240 PVRRQSYSRSRSRS 253
            |.:.||.|||||||
Frog   244 PGKSQSRSRSRSRS 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	37/71 (52%)
SF2	NP_001247139.1	RRM2_SRSF1_like	115..188	CDD:410013	31/74 (42%)
srsf6	NP_001001248.1	RRM1_SRSF6	3..72	CDD:241040	37/72 (51%)
		RRM2_SRSF4_like	106..176	CDD:241044	31/74 (42%)
		Rho	220..>403	CDD:333130	14/38 (37%)
		RRM	325..>453	CDD:330708
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000217
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000