Protein Alignment SF2 and srsf1b

DIOPT Version :10

• Sequence 1: NP_652611.1
• Gene: SF2 / 53443
• FlyBaseID: FBgn0283477
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_956887.2
• Gene: srsf1b / 393565
• ZFINID: ZDB-GENE-040426-1467
• Length: 245
• Species: Danio rerio
• Alignment Length: 255
• Identity: 160/255 - (62%)
• Similarity: 189/255 - (74%)
• Gaps: 28/255 - (10%)

  Fly     5 NECRIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRR-GPPFAFVEFEDARDADDAVKARDGYD 68
            |:||||||||||||||||::|:|:|:|.:..:|||||| |||||||||||.|||:|||..|||||
Zfish    13 NDCRIYVGNLPPDIRTKDVEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYD 77

  Fly    69 YDGYRLRVEFPRGGGPGSYRGGNRNDRSRDGGGRMG---GR-GPPAKRSQYRVMVTGLPASGSWQ 129
            ||||||||||||.|     |||.|..   .|||.:|   || |||::||:|||:|:|||.|||||
Zfish    78 YDGYRLRVEFPRSG-----RGGGRGG---GGGGGVGAPRGRYGPPSRRSEYRVIVSGLPPSGSWQ 134

  Fly   130 DLKDHMREAGDVCFADTYKDGSGVVEFLRHEDMKYAIKKLDDSRFRSHEGEVAYIRVREDSGDND 194
            |||||||||||||:||.::||:|||||:|.|||.||::|||:::|||||||.|||||:.|
Zfish   135 DLKDHMREAGDVCYADVFRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVD----- 194

  Fly   195 RGGGGGGSGGGGGGSGGGGSRDYRDRSRSRSFSSRPRR-RGTPTYSPVRRQSYSRSRSRS 253
                |..|...|.......||. |.||.|||.|..||| ||:|.|||    .:||||||:
Zfish   195 ----GPRSPSYGRSRSRSRSRS-RSRSNSRSRSYSPRRSRGSPRYSP----RHSRSRSRT 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_652611.1	RRM_SF	3..80	CDD:473069	59/75 (79%)
		RRM2_SRSF1_like	115..188	CDD:410013	55/72 (76%)
srsf1b	NP_956887.2	RRM1_SRSF1	11..89	CDD:410010	59/75 (79%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..116		15/34 (44%)
		RRM2_SRSF1	112..195	CDD:410160	61/91 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	192..245		27/66 (41%)