DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment SF2 and RBMY1J

DIOPT Version :9

Sequence 1:NP_001247139.1 Gene:SF2 / 53443 FlyBaseID:FBgn0283477 Length:255 Species:Drosophila melanogaster
Sequence 2:NP_001006117.2 Gene:RBMY1J / 378951 HGNCID:23917 Length:496 Species:Homo sapiens


Alignment Length:332 Identity:78/332 - (23%)
Similarity:114/332 - (34%) Gaps:98/332 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 RIYVGNLPPDIRTKDIQDLFHKFGKVTFVDL-KNR----RGPPFAFVEFEDARDADDAVKARDGY 67
            ::::|.|..:...|.::.:|.|.|.::.|.| |:|    ||  |||:.||:..||.:|.|..:|.
Human     9 KLFIGGLNRETNEKMLKAVFGKHGPISEVLLIKDRTSKSRG--FAFITFENPADAKNAAKDMNGT 71

  Fly    68 DYDGYRLRVE------FPRGG---GPGSYR-----GGNRNDRSRDGGGR-----------MGGRG 107
            ...|..::||      |..||   .|.|.|     |..|:.|...||.|           .||..
Human    72 SLHGKAIKVEQAKKPSFQSGGRRRPPASSRNRSPSGSLRSARGSSGGTRGWLPSHEGHLDDGGYT 136

  Fly   108 PPAKRSQYRVMV--------------------TGLPASGSWQDLKDHMREAGDVCFADTYKDGSG 152
            |..|.|..|.::                    :.:..|.||...:..|.:.         ::..|
Human   137 PDLKMSYSRGLIPVKRGPSSRSGGPPPKKSAPSAVARSNSWMGSQGPMSQR---------RENYG 192

  Fly   153 V------VEFLRHEDMK-----YAIKKLDDSRFRSHEGEVAYIRVREDSGDNDRGGGGGGSGGGG 206
            |      :...|::.|.     ||   .:|....|.:....|..........|.|..........
Human   193 VPPRRATISSWRNDRMSTRHDGYA---TNDGNHPSCQETRDYAPPSRGYAYRDNGHSNRDEHSSR 254

  Fly   207 G---------------GSGGGGSRDY----RDRSRSRSFSSRPRRRGTPTYSPVRR----QSYSR 248
            |               .|.|...|||    ||.|.||.:.:....|.|..|:|..|    :.|..
Human   255 GYRNHRSSRETRDYAPPSRGHAYRDYGHSRRDESYSRGYRNHRSSRETREYAPPSRGHGYRDYGH 319

  Fly   249 SRSRSNY 255
            ||...:|
Human   320 SRRHESY 326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SF2NP_001247139.1 RRM_SF 3..80 CDD:418427 26/82 (32%)
RRM2_SRSF1_like 115..188 CDD:410013 14/103 (14%)
RBMY1JNP_001006117.2 RRM <1..189 CDD:223796 47/190 (25%)
RRM_RBMX_like 7..85 CDD:240828 25/77 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 81..345 54/258 (21%)
dnaA 158..>316 CDD:333091 31/169 (18%)
RBM1CTR 174..218 CDD:311845 10/55 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 452..496
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.