DRSC/TRiP Functional Genomics Resources

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Protein Alignment SF2 and srsf5a

DIOPT Version :9

Sequence 1:NP_001247139.1 Gene:SF2 / 53443 FlyBaseID:FBgn0283477 Length:255 Species:Drosophila melanogaster
Sequence 2:NP_957161.1 Gene:srsf5a / 335396 ZFINID:ZDB-GENE-030131-7336 Length:259 Species:Danio rerio


Alignment Length:265 Identity:103/265 - (38%)
Similarity:140/265 - (52%) Gaps:32/265 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 CRIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRRGPPFAFVEFEDARDADDAVKARDGYDYDG 71
            ||:::|.|.|..|.:|::..|..:|::..::|||    .|.||||:|.|||||||...:|.:...
Zfish     4 CRVFIGRLSPHARERDVEKFFKGYGRIREINLKN----GFGFVEFDDYRDADDAVYELNGKELCS 64

  Fly    72 YRLRVEFP-----RGGGPGSYRGGNRNDR------SRDGGGRMGGRGPPAKRSQYRVMVTGLPAS 125
            .|:.:|..     ||||||  .||..:.|      ||.||.|.   |||. |:::|::|..|.:.
Zfish    65 ERVTIEHARSRRGRGGGPG--MGGRFSPRFGGYRQSRSGGSRY---GPPV-RTEHRIIVENLSSR 123

  Fly   126 GSWQDLKDHMREAGDVCFADTY--KDGSGVVEFLRHEDMKYAIKKLDDSRFRSHEGEVAYIRVRE 188
            .|||||||.||:.|:|.|.|.:  |...|||||..|.|||.||:|||.:.....:.::...|.|.
Zfish   124 ISWQDLKDLMRKVGEVTFVDAHRTKKNEGVVEFASHSDMKNAIEKLDGTDLNGRKLKLYEDRKRN 188

  Fly   189 DSGDNDRGGGGGGS-GGGGGGSGGGGSRDYRDRSRSRSFSSRPRRRGT----PTYSPVRRQSYSR 248
            .|....|......| ......|...||:    ||||||.|..|.::.|    |:.||..::..||
Zfish   189 RSRSRSRSRSSSRSRSPSRSRSPERGSK----RSRSRSLSRTPEKKSTSNRSPSRSPTPQRKQSR 249

  Fly   249 SRSRS 253
            |||.|
Zfish   250 SRSAS 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SF2NP_001247139.1 RRM_SF 3..80 CDD:418427 28/77 (36%)
RRM2_SRSF1_like 115..188 CDD:410013 32/74 (43%)
srsf5aNP_957161.1 RRM1_SRSF4_like 5..72 CDD:240783 27/70 (39%)
RRM2_SRSF4_like 113..184 CDD:241044 31/70 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0724
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000217
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1390
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
54.840

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