DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SF2 and Tia1

DIOPT Version :9

Sequence 1:	NP_001247139.1	Gene:	SF2 / 53443	FlyBaseID:	FBgn0283477	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_006236890.1	Gene:	Tia1 / 312510	RGDID:	1305742	Length:	387	Species:	Rattus norvegicus

Alignment Length:	204	Identity:	43/204 - (21%)
Similarity:	76/204 - (37%)	Gaps:	57/204 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SRNECRIYVGNLPPDIRTKDIQDLFHKFGKVT----FVDLKNRRGPPFAFVEFEDARDADDAVKA 63
            |::...::||:|.|:|.|:||:..|..||:::    ..|:...:...:.||.|.:..||::|::.
  Rat   103 SQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQ 167

  Fly    64 RDGYDYDGYRLRVEFPRGGGPGSYRGGNRNDRSRDGGGRMGGRGPPAKRSQYR------------ 116
            ..|....|.::|..:                         ..|.|||.:|.|.
  Rat   168 MGGQWLGGRQIRTNW-------------------------ATRKPPAPKSTYESNTKQLSYDEVV 207

  Fly   117 --------VMVTGLPASGSWQDLKDHMREA----GDVCFADTYKD-GSGVVEFLRHEDMKYAIKK 168
                    .:..|...||..:.|   ||:.    |.:.....:.| |...:.|..||...:||..
  Rat   208 SQSSPGNCTVYCGGVTSGLTEQL---MRQTFSPFGQIMEIRVFPDKGYSFIRFSSHESAAHAIVS 269

  Fly   169 LDDSRFRSH 177
            ::.:....|
  Rat   270 VNGTTIEGH 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	22/80 (28%)
SF2	NP_001247139.1	RRM2_SRSF1_like	115..188	CDD:410013	16/88 (18%)
Tia1	XP_006236890.1	ELAV_HUD_SF	6..281	CDD:273741	43/204 (21%)
		RRM_SF	8..82	CDD:302621
		RRM2_TIA1	106..185	CDD:241062	21/103 (20%)
		RRM3_TIAR	215..287	CDD:241064	15/67 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900