DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SF2 and Srsf5

DIOPT Version :9

Sequence 1:	NP_001247139.1	Gene:	SF2 / 53443	FlyBaseID:	FBgn0283477	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_038967784.1	Gene:	Srsf5 / 29667	RGDID:	3664	Length:	270	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	99/252 - (39%)
Similarity:	132/252 - (52%)	Gaps:	33/252 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CRIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRRGPPFAFVEFEDARDADDAVKARDGYDYDG 71
            ||:::|.|.|..|.||::..|..:|::..:|||  ||  |.||||||.|||||||...||.:...
  Rat     4 CRVFIGRLNPAAREKDVERFFKGYGRIRDIDLK--RG--FGFVEFEDPRDADDAVYELDGKELCS 64

  Fly    72 YRLRVEFPRGGGPGSYRGGNRNDRSRDGGGRMGGRGPPAKRSQYRVMVTGLPASGSWQDLKDHMR 136
            .|:.:|..|....|....|..:||......|...|..|..|::.|::|..|.:..|||||||.||
  Rat    65 ERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMR 129

  Fly   137 EAGDVCFADTY--KDGSGVVEFLRHEDMKYAIKKLDDSRFRSHEGEVAYIRVREDSGDNDRGGGG 199
            :||:|.|||.:  |...|||||..:.|:|.||:||........:     |::.|.|..:.|
  Rat   130 QAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRK-----IKLIEGSKRHSR---- 185

  Fly   200 GGSGGGGGGSGGGGSRDYRDRSRSRSFS---SRPRRRGTPTYSPVRRQSYSRSRSRS 253
                          ||. |.|||:||.|   ||.|.|.:.:||..|.:|.|||:|||
  Rat   186 --------------SRS-RSRSRTRSSSRSRSRSRSRRSKSYSRSRSRSRSRSKSRS 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	33/72 (46%)
SF2	NP_001247139.1	RRM2_SRSF1_like	115..188	CDD:410013	31/74 (42%)
Srsf5	XP_038967784.1	RRM1_SRSF5	5..74	CDD:410008	32/72 (44%)
Srsf5	XP_038967784.1	RRM2_SRSF5	99..179	CDD:410158	34/84 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000217
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810