Protein Alignment SF2 and Srsf5

DIOPT Version :10

• Sequence 1: NP_652611.1
• Gene: SF2 / 53443
• FlyBaseID: FBgn0283477
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_001334344.1
• Gene: Srsf5 / 20384
• MGIID: 98287
• Length: 270
• Species: Mus musculus
• Alignment Length: 252
• Identity: 99/252 - (39%)
• Similarity: 132/252 - (52%)
• Gaps: 33/252 - (13%)

  Fly     7 CRIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRRGPPFAFVEFEDARDADDAVKARDGYDYDG 71
            ||:::|.|.|..|.||::..|..:|::..:|||  ||  |.||||||.|||||||...||.:...
Mouse     4 CRVFIGRLNPAAREKDVERFFKGYGRIRDIDLK--RG--FGFVEFEDPRDADDAVYELDGKELCS 64

  Fly    72 YRLRVEFPRGGGPGSYRGGNRNDRSRDGGGRMGGRGPPAKRSQYRVMVTGLPASGSWQDLKDHMR 136
            .|:.:|..|....|....|..:||......|...|..|..|::.|::|..|.:..|||||||.||
Mouse    65 ERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMR 129

  Fly   137 EAGDVCFADTY--KDGSGVVEFLRHEDMKYAIKKLDDSRFRSHEGEVAYIRVREDSGDNDRGGGG 199
            :||:|.|||.:  |...|||||..:.|:|.||:||........:     |::.|.|..:.|
Mouse   130 QAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRK-----IKLIEGSKRHSR---- 185

  Fly   200 GGSGGGGGGSGGGGSRDYRDRSRSRSFS---SRPRRRGTPTYSPVRRQSYSRSRSRS 253
                          ||. |.|||:||.|   ||.|.|.:.:||..|.:|.|||:|||
Mouse   186 --------------SRS-RSRSRTRSSSRSRSRSRSRRSKSYSRSRSRSRSRSKSRS 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_652611.1	RRM_SF	3..80	CDD:473069	33/72 (46%)
		RRM2_SRSF1_like	115..188	CDD:410013	31/74 (42%)
Srsf5	NP_001334344.1	RRM1_SRSF5	5..74	CDD:410008	32/72 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..105		8/31 (26%)
		RRM2_SRSF5	99..179	CDD:410158	34/84 (40%)