Protein Alignment SF2 and Ncl

DIOPT Version :10

• Sequence 1: NP_652611.1
• Gene: SF2 / 53443
• FlyBaseID: FBgn0283477
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_035010.3
• Gene: Ncl / 17975
• MGIID: 97286
• Length: 707
• Species: Mus musculus
• Alignment Length: 240
• Identity: 62/240 - (25%)
• Similarity: 99/240 - (41%)
• Gaps: 53/240 - (22%)

  Fly     9 IYVGNLPPDIRTKDIQDLFHKFGKVTFVDL-KNRRGPP--FAFVEFEDARDADDAVKARDGYDYD 70
            :.:.||......:.::::|.   |.||:.: :|..|.|  :||:||....||.:|:.:.:..:.:
Mouse   489 LVLSNLSYSATKETLEEVFE---KATFIKVPQNPHGKPKGYAFIEFASFEDAKEALNSCNKMEIE 550

  Fly    71 GYRLRVEFPRGGGPGSYRGGNRNDRSRDGGGRMGGRGPPAKRSQYRVMVTGLPASGSWQDLKDHM 135
            |..:|:|.         :|.|             .|..|:|    .:.|.||....:.:.||:..
Mouse   551 GRTIRLEL---------QGSN-------------SRSQPSK----TLFVKGLSEDTTEETLKESF 589

  Fly   136 -----------REAGDVCFADTYKDGSGVVEFLRHEDMKYAIKKLDDSRFRSHEGEVAYIRVRED 189
                       ||.|.       ..|.|.|:|...||.|.|.:.::|.....::..:.:.:.:.:
Mouse   590 EGSVRARIVTDRETGS-------SKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 647

  Fly   190 SGDNDRGGGGGGSGGGGGGSGGGGSRDYRDRSRSRSFSSRPRRRG 234
            .|...||||.||.||.|||.||.|....|.|.   .|..|...||
Mouse   648 GGFGGRGGGRGGFGGRGGGRGGRGGFGGRGRG---GFGGRGGFRG 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_652611.1	RRM_SF	3..80	CDD:473069	19/73 (26%)
		RRM2_SRSF1_like	115..188	CDD:410013	17/83 (20%)
Ncl	NP_035010.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..308
		PRK13808	<12..142	CDD:172341
		8 X 8 AA tandem repeats of X-T-P-X-K-K-X-X	58..135
		RRM1_NCL	309..383	CDD:409837
		RRM2_NCL	392..467	CDD:409838
		RRM3_NCL	486..558	CDD:409839	18/71 (25%)
		RRM4_NCL	569..646	CDD:409840	18/87 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	639..707		21/54 (39%)