DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SF2 and tiar-2

DIOPT Version :9

Sequence 1:	NP_001247139.1	Gene:	SF2 / 53443	FlyBaseID:	FBgn0283477	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_496718.1	Gene:	tiar-2 / 174909	WormBaseID:	WBGene00012904	Length:	434	Species:	Caenorhabditis elegans

Alignment Length:	255	Identity:	72/255 - (28%)
Similarity:	116/255 - (45%)	Gaps:	38/255 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IYVGNLPPDIRTKDIQDLFHKFGKVT----FVDLKNRRGPPFAFVEFEDARDADDAVKARDGYDY 69
            ::||:|..:|.:..:::.|.|||:|:    ..|....:|..:.||.:....||:.|:...:|...
Worm   134 VFVGDLCSEIDSTKLREAFVKFGEVSEAKIIRDNNTNKGKGYGFVSYPRREDAERAIDEMNGAWL 198

  Fly    70 DGYRLRVEF-PRGGGPGSYRGGNRNDRSRDGGGRMGGRGPPAKRSQ--YRVMVTGLPAS------ 125
            ....:|..: .|.......|||:|.|| |.|||  |||.....:|:  |..:.....|.
Worm   199 GRRTIRTNWATRKPDEDGERGGDRGDR-RGGGG--GGRDRYHNQSEKTYDEIFNQAAADNTSVYV 260

  Fly   126 GSWQDL-KDHMREA----GDVCFADTYK-DGSGVVEFLRHEDMKYAIKKLDDSRFRSHEGEVAYI 184
            |:..:| :|.:|.|    |.:....|:| .|...|:|...|....||.:::::.........::.
Worm   261 GNIANLGEDEIRRAFDRFGPINEVRTFKIQGYAFVKFETKESAARAIVQMNNADIGGQIVRCSWG 325

  Fly   185 RVREDSGDNDRG-GGGGGSG---------GGGGGSGGGGSRDYRDRSRSRSFSSRPRRRG 234
            :..:....::|| |||||||         ||||||||.|:      |:..:|:.||...|
Worm   326 KSGDSGKPSERGSGGGGGSGNYGYGYGNSGGGGGSGGPGN------SQFSNFNQRPPPSG 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	18/75 (24%)
SF2	NP_001247139.1	RRM2_SRSF1_like	115..188	CDD:410013	16/84 (19%)
tiar-2	NP_496718.1	RRM	36..321	CDD:223796	49/189 (26%)
		RRM_SF	42..113	CDD:302621
		RRM_SF	133..207	CDD:302621	18/72 (25%)
		RRM3_TIA1_like	256..326	CDD:240800	14/69 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810