DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SF2 and rsp-1

DIOPT Version :9

Sequence 1:	NP_001247139.1	Gene:	SF2 / 53443	FlyBaseID:	FBgn0283477	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_496442.1	Gene:	rsp-1 / 174748	WormBaseID:	WBGene00004698	Length:	312	Species:	Caenorhabditis elegans

Alignment Length:	273	Identity:	101/273 - (36%)
Similarity:	135/273 - (49%)	Gaps:	46/273 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRRGPPFAFVEFEDARDADDAVKARDGYDYDGY 72
            |||:|.|...:..|||:..|..:|::..|.|||    .|.||||:|.|||:|||...:|.:..|.
Worm     4 RIYIGRLTSRVSEKDIEHFFRGYGQIRDVLLKN----GFGFVEFDDKRDAEDAVHDLNGKELGGE 64

  Fly    73 RLRVEF--PRGGG------PGSYRGGNRNDRSRDGGGRMGG--------RGPPAKRSQY------ 115
            |:.:::  |||||      .|..|||.|......|||  ||        ||||.:.|:|
Worm    65 RVILDYSKPRGGGGDRGGFGGGGRGGARVSSYSGGGG--GGRDRFDRYDRGPPRRESRYGRPYST 127

  Fly   116 --RVMVTGLPASGSWQDLKDHMREAG-DVCFADTYK-DGSGVVEFLRHEDMKYAIKKLDDSRFRS 176
              ||:|..|.:..|||||||.:|..| :..:|:.:| ....::.|....|:|..|:|.|......
Worm   128 RHRVVVENLSSRISWQDLKDQVRRQGVEPTYAEAHKRPNEALLCFATPSDLKRCIEKCDGMDLNG 192

  Fly   177 HEGEVAYIRVREDSGDNDRGGGGGGSGGGGGGSGGGGSRDYRDRSRSRSFS-SRPRRRGTPTYSP 240
            .:     |::.:||     ..|...|...........||| |.||||||.| |:.|.|..|..|
Worm   193 RK-----IKMIDDS-----QAGRSRSRSNSRSRSRSRSRD-RRRSRSRSSSRSKSRSRSPPKRS- 245

  Fly   241 VRRQSYSRSRSRS 253
             ||:|.|:|||||
Worm   246 -RRESKSKSRSRS 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	29/73 (40%)
SF2	NP_001247139.1	RRM2_SRSF1_like	115..188	CDD:410013	23/82 (28%)
rsp-1	NP_496442.1	RRM	<3..180	CDD:223796	67/181 (37%)
		RRM1_SRSF4_like	4..73	CDD:240783	29/72 (40%)
		RRM2_SRSF4_like	129..200	CDD:241044	22/75 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000217
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1390
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940