Protein Alignment SF2 and SRSF10

DIOPT Version :10

• Sequence 1: NP_652611.1
• Gene: SF2 / 53443
• FlyBaseID: FBgn0283477
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_473357.1
• Gene: SRSF10 / 10772
• HGNCID: 16713
• Length: 262
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 61/261 - (23%)
• Similarity: 106/261 - (40%)
• Gaps: 39/261 - (14%)

  Fly     9 IYVGNLPPDIRTKDIQDLFHKFGKVTFV----DLKNRRGPPFAFVEFEDARDADDAVKARDGYDY 69
            ::|.|:..|.|::|::..|.::|.:..|    |...||...||:|:|||.|||:||:...|....
Human    12 LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWI 76

  Fly    70 DGYRLRVEFPRGG-----------GPGSYRGGNRNDRSRDGGGRMGGRGPPAKRSQYRVMVTGLP 123
            .|.::.::|.:|.           |...|.....:|..|....|  .|....:||:.|.......
Human    77 CGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR--SRSYERRRSRSRSFDYNYR 139

  Fly   124 ASGSWQDLKDHMREAGDVCFADTYKDGSGVVEFLRHEDMKYAIKKLDD-SRFRSHEGEVAYIRVR 187
            .|.|    ..:.|..|....:.::.|.    :..:|.:..::..|.:. ||.:|...:....:.|
Human   140 RSYS----PRNSRPTGRPRRSRSHSDN----DRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSR 196

  Fly   188 EDSGDNDRGGGGGGSGGGGGGSGGGGSRDYRDRSRSRSFSSRPRRRGTPTYSPVRRQSYSRSRSR 252
            ..|..:.:             :.|....|.:...:|.|...:..|:..|..|..:.:|.|||||:
Human   197 SRSASHTK-------------TRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSK 248

  Fly   253 S 253
            |
Human   249 S 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_652611.1	RRM_SF	3..80	CDD:473069	25/74 (34%)
		RRM2_SRSF1_like	115..188	CDD:410013	11/73 (15%)
SRSF10	NP_473357.1	RRM_SF	5..99	CDD:473069	26/86 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..262		31/157 (20%)