DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SF2 and hnrnpm

DIOPT Version :9

Sequence 1:	NP_001247139.1	Gene:	SF2 / 53443	FlyBaseID:	FBgn0283477	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_004911113.1	Gene:	hnrnpm / 100489127	XenbaseID:	XB-GENE-993962	Length:	744	Species:	Xenopus tropicalis

Alignment Length:	313	Identity:	75/313 - (23%)
Similarity:	101/313 - (32%)	Gaps:	126/313 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RIYVGNLPPDIRTKDIQDLF-HKFGKVTFVDL------KNRRGPPFAFVEFEDARDADDAVKARD 65
            |.::.|:|.|::.:.::||. .|.|:||:|:|      |:|   ..|.|||:.......||:..:
Frog    74 RAFISNIPFDVKWQALKDLVKEKVGEVTYVELLMDDEGKSR---GCAAVEFKLEDSMKKAVQVLN 135

  Fly    66 GYDYDGYRLRV-EFPRG----------------------------------------GGPGSYRG 89
            .:..:|..|:| |.|.|                                        ||||....
Frog   136 KHVLNGRPLKVREDPDGERSRRAAHSVFGPGPMGMGGPGPMGMGGPGPMGMPGPMGMGGPGPIGL 200

  Fly    90 GNRNDRSRDGGGRMGGRGPP-----------------AKRSQYRVMVTGLPASGSWQDLKDHMRE 137
            |........|.|.:||..||                 |.|....|.|..|..|..|:.||:....
Frog   201 GGPGPLGMGGPGPVGGNIPPSLLNNPNIPREVIHALQAGRLGSTVFVANLDYSVGWKKLKEVFGI 265

  Fly   138 AGDVCFADTYKD------GSGVVEFLRHEDMKYAIK--------------KLDDSRFRSHEGEVA 182
            ||.|..||..:|      |.|.|.:.:..:...||.              |:||...
Frog   266 AGTVVRADVLEDKDGKSRGIGTVTYEQPIEAVQAISMFNGQPLFDRPMMVKMDDKSM-------- 322

  Fly   183 YIRVREDSGD---NDR--------GGGGGGSGGGG-------------GGSGG 211
                  ..||   .||        ||.|.|.|.||             ||.||
Frog   323 ------PKGDLFPADRPPQLPRGLGGIGMGLGPGGQPIDANHLRGSTMGGPGG 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	24/79 (30%)
SF2	NP_001247139.1	RRM2_SRSF1_like	115..188	CDD:410013	21/92 (23%)
hnrnpm	XP_004911113.1	HnRNP_M	48..72	CDD:371586
		RRM1_hnRNPM	74..149	CDD:241101	23/77 (30%)
		PABP-1234	76..>388	CDD:130689	74/311 (24%)
		RRM2_hnRNPM_like	245..318	CDD:240832	19/72 (26%)
		RRM3_hnRNPM	668..744	CDD:241105
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910