DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SF2 and srsf4

DIOPT Version :9

Sequence 1:	NP_001247139.1	Gene:	SF2 / 53443	FlyBaseID:	FBgn0283477	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_004911639.2	Gene:	srsf4 / 100038227	XenbaseID:	XB-GENE-493077	Length:	741	Species:	Xenopus tropicalis

Alignment Length:	250	Identity:	97/250 - (38%)
Similarity:	127/250 - (50%)	Gaps:	25/250 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLKNRRGPPFAFVEFEDARDADDAVKARDGYDYDGY 72
            |:|:|.|....|.:|::..|..|||:..|||||..|    ||||||:|||:|||...:|.:..|.
Frog     8 RVYIGRLSHRARERDVERFFKGFGKIVEVDLKNGYG----FVEFEDSRDAEDAVYEMNGRELCGE 68

  Fly    73 RLRVEFPRGGGPGSYRGGNRNDRSRDGGGRMGGR---GPPAKRSQYRVMVTGLPASGSWQDLKDH 134
            |:.||..|         ..|.|.....|.|.||.   |||. |:.||:.|..|.:..|||||||.
Frog    69 RVIVEHAR---------APRRDIRSGYGYRKGGSDKYGPPV-RTMYRLRVENLSSRCSWQDLKDF 123

  Fly   135 MREAGDVCFADTY--KDGSGVVEFLRHEDMKYAIKKLDDSRFRSHEGEVAYIRVREDSGDNDRGG 197
            ||:||:|.:||.:  :...||:||..:.||:.|::|||.|.....:     |::.||.. ..|..
Frog   124 MRQAGEVTYADAHQRRQNEGVIEFRSYSDMRRALEKLDGSEINGRK-----IQLVEDRA-GSRNK 182

  Fly   198 GGGGSGGGGGGSGGGGSRDYRDRSRSRSFSSRPRRRGTPTYSPVRRQSYSRSRSR 252
            |..........|....|...|.||||||.|...:|..:.:.|..||.|.|.||.|
Frog   183 GSSSRSRSRSRSRRSRSSHSRSRSRSRSHSRSRQRERSRSRSKERRSSRSHSRKR 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	33/71 (46%)
SF2	NP_001247139.1	RRM2_SRSF1_like	115..188	CDD:410013	30/74 (41%)
srsf4	XP_004911639.2	RRM_SF	6..77	CDD:418427	34/81 (42%)
		RRM_SF	104..176	CDD:418427	31/76 (41%)
		ser_rich_anae_1	<249..>456	CDD:411418
		PRK12678	352..>573	CDD:237171
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000217
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910