Protein Alignment pont and ruvbl2

DIOPT Version :10

• Sequence 1: NP_652608.1
• Gene: pont / 53439
• FlyBaseID: FBgn0040078
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: XP_012821814.1
• Gene: ruvbl2 / 448144
• XenbaseID: XB-GENE-483344
• Length: 462
• Species: Xenopus tropicalis
• Alignment Length: 456
• Identity: 205/456 - (44%)
• Similarity: 305/456 - (66%)
• Gaps: 15/456 - (3%)

  Fly     2 KIEEVKSTVRTQRIAAHSHVKGLGLDEVGAAVHSAAGLVGQKAAREAAGIVVDLIKSKKMAGRAL 66
            |:.||:...|.:||.||||::|||||:.......:.|:|||.|||.|||:::::||..|:||||:
 Frog     8 KVPEVRDVTRIERIGAHSHIRGLGLDDALEPRQVSQGMVGQLAARRAAGVILEMIKEGKIAGRAV 72

  Fly    67 LLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVFSNEIKKTEVLMENFRRSIGLRIRETKEVY 131
            |:||.|||||||||:.:||.||:..||..:.|||:||.|:.|||.|.:.||||||:||:|..|:.
 Frog    73 LIAGQPGTGKTAIAMGMAQALGSDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEII 137

  Fly   132 EGEVTELTPVETENPMGGYGKTISNVVIGLKTAKGTKQLKLDPSIFDALQKEKVEVGDVIYIEAN 196
            ||||.|   |:.:.|..|.|..:..:.  |||.:......|...:.::|.||||:.||||.|:..
 Frog   138 EGEVVE---VQIDRPATGTGAKVGKLT--LKTTEMETIYDLGTKMIESLTKEKVQAGDVITIDKA 197

  Fly   197 SGAVKRQGRSDTFATEFDL--ETEEYVPLPKGDVHKKKEVIQDVTLHDLDVANARPQGGQDVLSM 259
            :|.:.:.||:.|.|.::|.  ...::|..|.|::.|:|||:..|:||::||.|:|.||
 Frog   198 TGKITKLGRAFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQG------- 255

  Fly   260 MGQLMKPKKTEITDKLRMEINKVVNKYIDQGIAELVPGVLFIDEIHMLDLETFTYLHKSLESPIA 324
            ...|......||..::|.:||..|.::.::|.||::||||||||:||||:|.|::|:::|||.:|
 Frog   256 FLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIECFSFLNRALESDMA 320

  Fly   325 PIVIFATNRGRCVIRGTTDIVSPHGIPLDLLDRLLIIRTLLYSTADMEQIIKLRAQTEGLQLEEN 389
            |::|.|||||...||| |:..||||||:|||||||||.|..|:..:.:||:|:|.:.|.:.:.|:
 Frog   321 PVLIMATNRGITRIRG-TNYQSPHGIPIDLLDRLLIISTSPYNEKETKQILKIRCEEEDVDMTED 384

  Fly   390 AFTRLSEIGTSSTLRYAVQLLTPAHQMCKVNGRNQISKDDIEDVHSLFLDAKRSSKHLSEKNNKF 454
            |:|.|:.||..::|||::||:|.|..:|:.....::..|||:.|:|||||..||::::.|..:.|
 Frog   385 AYTVLTRIGLETSLRYSMQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAF 449

  Fly   455 M 455
            |
 Frog   450 M 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pont	NP_652608.1	TIP49	14..351	CDD:399217	155/338 (46%)
		TIP49_C	374..439	CDD:436097	25/64 (39%)
ruvbl2	XP_012821814.1	TIP49	20..364	CDD:399217	168/356 (47%)
		TIP49_C	369..434	CDD:436097	25/64 (39%)