Protein Alignment pont and Ruvbl2

DIOPT Version :10

• Sequence 1: NP_652608.1
• Gene: pont / 53439
• FlyBaseID: FBgn0040078
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_035434.1
• Gene: Ruvbl2 / 20174
• MGIID: 1342299
• Length: 463
• Species: Mus musculus
• Alignment Length: 456
• Identity: 203/456 - (44%)
• Similarity: 307/456 - (67%)
• Gaps: 15/456 - (3%)

  Fly     2 KIEEVKSTVRTQRIAAHSHVKGLGLDEVGAAVHSAAGLVGQKAAREAAGIVVDLIKSKKMAGRAL 66
            |:.|::...|.:||.||||::|||||:......::.|:|||.|||.|||:|:::|:..|:||||:
Mouse     9 KVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAV 73

  Fly    67 LLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVFSNEIKKTEVLMENFRRSIGLRIRETKEVY 131
            |:||.|||||||||:.:||.||...||..:.|||:||.|:.|||.|.:.||||||:||:|..|:.
Mouse    74 LIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEII 138

  Fly   132 EGEVTELTPVETENPMGGYGKTISNVVIGLKTAKGTKQLKLDPSIFDALQKEKVEVGDVIYIEAN 196
            ||||.|   ::.:.|..|.|..:..:.  |||.:......|...:.::|.|:||:.||||.|:..
Mouse   139 EGEVVE---IQIDRPATGTGSKVGKLT--LKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKA 198

  Fly   197 SGAVKRQGRSDTFATEFDL--ETEEYVPLPKGDVHKKKEVIQDVTLHDLDVANARPQGGQDVLSM 259
            :|.:.:.|||.|.|.::|.  ...::|..|.|::.|:|||:..|:||::||.|:|.||
Mouse   199 TGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQG------- 256

  Fly   260 MGQLMKPKKTEITDKLRMEINKVVNKYIDQGIAELVPGVLFIDEIHMLDLETFTYLHKSLESPIA 324
            ...|......||..::|.:||..|.::.::|.||::||||||||:||||:|:|::|:::|||.:|
Mouse   257 FLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMA 321

  Fly   325 PIVIFATNRGRCVIRGTTDIVSPHGIPLDLLDRLLIIRTLLYSTADMEQIIKLRAQTEGLQLEEN 389
            |::|.|||||...||||: ..||||||:||||||||:.|..||..|.:||:::|.:.|.:::.|:
Mouse   322 PVLIMATNRGITRIRGTS-YQSPHGIPIDLLDRLLIVSTSPYSEKDTKQILRIRCEEEDVEMSED 385

  Fly   390 AFTRLSEIGTSSTLRYAVQLLTPAHQMCKVNGRNQISKDDIEDVHSLFLDAKRSSKHLSEKNNKF 454
            |:|.|:.||..::||||:||:|.|..:|:.....::..|||:.|:|||||..||::::.|..:.|
Mouse   386 AYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAF 450

  Fly   455 M 455
            :
Mouse   451 L 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pont	NP_652608.1	TIP49	14..351	CDD:399217	154/338 (46%)
		TIP49_C	374..439	CDD:436097	25/64 (39%)
Ruvbl2	NP_035434.1	TIP49	21..365	CDD:399217	167/356 (47%)
		TIP49_C	370..435	CDD:436097	25/64 (39%)