DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RecQ4 and RECQL2

DIOPT Version :9

Sequence 1:	NP_652607.1	Gene:	RecQ4 / 53438	FlyBaseID:	FBgn0040290	Length:	1579	Species:	Drosophila melanogaster
Sequence 2:	NP_174421.3	Gene:	RECQL2 / 840026	AraportID:	AT1G31360	Length:	739	Species:	Arabidopsis thaliana

Alignment Length:	529	Identity:	168/529 - (31%)
Similarity:	243/529 - (45%)	Gaps:	109/529 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   735 RLPQAANAAILQGDELNESEEDDQESSGDEEVQQHPDPNWSSDEMDVDFEALDAAVEASLSQPVS 799
            |..:..:||:....|..|||      :..|::|          .:||:.:.:...:.|.:.....
plant    19 RRRKGKHAAVDSAGESMESE------AIQEDLQ----------NLDVELKDVQGQISALIEHQDR 67

  Fly   800 QEKAASPIKTYVGHKIPEEFLKQAGLDTTASSSNRSQHGGVKPLYDLLPDGSVQDTTPEVLE--- 861
            ..:..|.:||         .||.    ..||.|..:..||          .|..:...|..|
plant    68 LYERKSELKT---------LLKA----LAASGSPVASSGG----------SSAIENWSETFEWDS 109

  Fly   862 -----ALHMFGHTNFRKGQDRAIMRTLSGLSSLVTLSTGSGKSLCYQLPAYLYSRKVGAITLVIS 921
                 ..::||.:.:|..|...|...::|...||.::.|.||||||||||.|.    |..|||:|
plant   110 RADDVRFNVFGISKYRANQKEIINAIMTGRDVLVIMAAGGGKSLCYQLPAMLR----GGTTLVVS 170

  Fly   922 PLVSLMEDQVTGVPHF-LRAHCLHTNQTAPQRMKIQQMIANGEID--ILLVSPEAVVAGERATGF 983
            ||:||::|||.|:... :.|:.|.:.........:.:.:..||.|  ||.|:||.|...:|....
plant   171 PLLSLIQDQVMGLAALGISAYMLTSTSGKENEKFVYKALEKGEDDLKILYVTPEKVSKSKRFMSK 235

  Fly   984 GAILRQLPPIAFACIDEAHCVSQWSHNFRPSYLMICKVLRKNLGV-RT------VLGLTATATLP 1041
            .........::...||||||.|||.|:|||.|        |||.: :|      ::.||||||..
plant   236 LEKCHNAGRLSLISIDEAHCCSQWGHDFRPDY--------KNLSILKTQFPKVPMVALTATATQK 292

  Fly  1042 TRVSIINHLGISDGERGIISDIPLPDNLVLSVSK---------DENRDAALLQLLNSERFEPCQS 1097
            .:..:|..|.|....: .:|.:..| ||..||.:         ||     :.:.:. |.:...:|
plant   293 VQNDLIEMLHIPKCVK-FVSSVNRP-NLFYSVREKSAVGKLVVDE-----IAEFIR-ESYSNNES 349

  Fly  1098 IIIYCTRRDECERIAGFIRTCVQDRREPTQDQTKKRKRVNWQAEPYHAGMPASRRRTVQKAFMSN 1162
            .|:||..|.|||:|||       |.||.           ...|:.|||.|.|:.|..|...:..|
plant   350 GIVYCFSRKECEQIAG-------DLRER-----------GISADYYHADMDANMREKVHMRWSKN 396

  Fly  1163 ELRIVVATIAFGMGINKPDIRAVIHYNMPRNFESYVQEIGRAGRDGLPSHCHLFLDAKGGD---Q 1224
            :|:::|.|:||||||||||:|.|||:::.::.|:|.||.||||||||||.|.||.  :..|   |
plant   397 KLQVIVGTVAFGMGINKPDVRFVIHHSLSKSMETYYQESGRAGRDGLPSECILFF--RSADVPRQ 459

  Fly  1225 SELRRHVYS 1233
            |.:..:.||
plant   460 SSMVFYEYS 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RecQ4	NP_652607.1	RecQL4_SLD2_NTD	9..55	CDD:421279
RecQ4	NP_652607.1	RecQ	864..>1218	CDD:223588	138/372 (37%)
RECQL2	NP_174421.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0514
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D445763at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820