| Sequence 1: | NP_652607.1 | Gene: | RecQ4 / 53438 | FlyBaseID: | FBgn0040290 | Length: | 1579 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000544.2 | Gene: | WRN / 7486 | HGNCID: | 12791 | Length: | 1432 | Species: | Homo sapiens |
| Alignment Length: | 803 | Identity: | 220/803 - (27%) |
|---|---|---|---|
| Similarity: | 326/803 - (40%) | Gaps: | 213/803 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 542 PLNPEDLKYVLALE--AGDITSVPRINVQDLEEADATAQRYI-----RTFAAGPNPGLSEGSNIR 599
Fly 600 VD--EKRAAARKKLEE----RIAAGKLNENFVTINIQKKKFVRGKKSVNFSKYKKQQWRHKKRVA 658
Fly 659 ALSGPDMDMGGCDGGVLTCFQCGGVGHFAQQCKVKGDSLLPLSAQLEEDPSPFPTL--------- 714
Fly 715 ------AEAQEMASQGAVVAHSRNISRLPQAANAAILQGDELNESEEDDQESSGDEEV------- 766
Fly 767 -QQHPDPNWSSDEMDVDF-----EALDAAVEASLSQPVSQEKAASPIKTYV---GHKIPEEFLKQ 822
Fly 823 AGLDTTASSSNRSQHGGVKPLYDL---------LP-------------DGSVQD--------TTP 857
Fly 858 EVLEALHM-FGHTNFRKGQDRAIMRTL-SGLSSLVTLSTGSGKSLCYQLPAYLYSRKVGAITLVI 920
Fly 921 SPLVSLMEDQV-----TGVPH-FLRAHCLHTNQTAPQRMKIQQMIANGEIDILLVSPEAVVAGER 979
Fly 980 ATGFGAILRQLPP---IAFACIDEAHCVSQWSHNFRPSYLMICKVLRKNLGVRTVLGLTATATLP 1041
Fly 1042 TRVSIINHLGISDGE---RGIISDIPLPDNLVLSVSKDENRDAALLQLL------NSERFEPCQS 1097
Fly 1098 IIIYCTRRDECERIAGFIRTCVQDRREPTQDQTKKRKRVNWQAEPYHAGMPASRRRTVQKAFMSN 1162
Fly 1163 ELRIVVATIAFGMGINKPDIRAVIHYNMPRNFESYVQEIGRAGRDGLPSHCH-LFLDAKGGDQSE 1226
Fly 1227 LRRHVYSNSIDRHVIRKLLQKIF 1249 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RecQ4 | NP_652607.1 | RecQL4_SLD2_NTD | 9..55 | CDD:421279 | |
| RecQ | 864..>1218 | CDD:223588 | 137/374 (37%) | ||
| WRN | NP_000544.2 | Interaction with WRNIP1. /evidence=ECO:0000250 | 2..277 | 22/79 (28%) | |
| RNaseD_like | 61..229 | CDD:176650 | 10/31 (32%) | ||
| 2 X 27 AA tandem repeats of H-L-S-P-N-D-N-E-N-D-T-S-Y-V-I-E-S-D-E-D-L-E-M-E-M-L-K | 424..477 | 15/59 (25%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 498..529 | 4/30 (13%) | |||
| recQ_fam | 538..1010 | CDD:129701 | 142/410 (35%) | ||
| DEAD | 551..712 | CDD:278688 | 62/180 (34%) | ||
| DEAH box | 668..671 | 2/2 (100%) | |||
| HELICc | 759..867 | CDD:238034 | 55/125 (44%) | ||
| RecQ_Zn_bind | 872..939 | CDD:292742 | 3/17 (18%) | ||
| RQC | 958..1051 | CDD:214936 | |||
| Interaction with DNA. /evidence=ECO:0000269|PubMed:20159463 | 987..993 | ||||
| HRDC | 1156..1229 | CDD:128635 | |||
| HTH_40 | 1261..1351 | CDD:291179 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG0514 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D445763at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||