Protein Alignment RecQ4 and RecQ5

DIOPT Version :10

• Sequence 1: NP_652607.1
• Gene: RecQ4 / 53438
• FlyBaseID: FBgn0040290
• Length: 1579
• Species: Drosophila melanogaster
• Sequence 2: NP_729983.1
• Gene: RecQ5 / 39594
• FlyBaseID: FBgn0027375
• Length: 1058
• Species: Drosophila melanogaster
• Alignment Length: 536
• Identity: 158/536 - (29%)
• Similarity: 240/536 - (44%)
• Gaps: 114/536 - (21%)

  Fly   859 VLEALHM-FGHTNFRKG-QDRAIMRTLSGLSSL-VTLSTGSGKSLCYQLPAYLYSRKVGAITLVI 920
            |.|||.. |||:.|:.. |::|:...:.....: |::.||||||||:|||..:...:   ||:|.
  Fly     7 VHEALKKHFGHSKFKSDLQEKAVKCAVKKKQDVYVSMPTGSGKSLCFQLPGLMSENQ---ITIVF 68

  Fly   921 SPLVSLMEDQVTGVPHFLR----AHCLHTNQTAPQR----MKIQQMIANGEIDILLVSPEAVVAG 977
            |||::|::||   :.|..:    |..|::..:..:|    |.::.:..|  :..|.::||
  Fly    69 SPLLALIKDQ---IDHLTKLKVPADSLNSKMSTKERDRVIMDLKAVRTN--LKFLYITPE----- 123

  Fly   978 ERATGFGAILRQL----PPIAFACIDEAHCVSQWSHNFRPSYLMICKVLRKNLGVRTVLGLTATA 1038
            :.||.|...|.|.    ..:|:..:|||||||||.|:|||.||.:.: ||........|.|||||
  Fly   124 QAATKFFQDLLQTLHKHNKLAYFAVDEAHCVSQWGHDFRPDYLKLGE-LRSKYSDVIWLALTATA 187

  Fly  1039 TLPTRVSIINHLGISDG---------ERGIISDIPLPDNLVLSVSKDENR--DAALLQLLNSERF 1092
            :...:..|...|.:...         .:.:..||...:    |:..|...  |.|...|.|.:.|
  Fly   188 SREVKEDIYKQLRLHQPVAQFSTPSFRKNLFYDIVYKN----SIEDDFQHLADFARHCLGNPKEF 248

  Fly  1093 EP-------CQSIIIYCTRRDECERIAGFIRTCVQDRREPTQDQTKKRKRVNWQAEPYHAGMPAS 1150
            :.       |.  |:||..||:.||:|..:              ||:    ...|..||||:...
  Fly   249 KDTPKPQRGCG--IVYCRTRDQVERMAIGV--------------TKQ----GIGAVAYHAGLKTG 293

  Fly  1151 RRRTVQKAFMSNELRIVVATIAFGMGINKPDIRAVIHYNMPRNFESYVQEIGRAGRDGLPSHCHL 1215
            .|..||:|:|..:..|:.||.:||||::||.:|.|||:::|:|..:|.||.||||||||.|:|.|
  Fly   294 ERTEVQEAWMRGDQPIICATNSFGMGVDKPSVRFVIHWDVPQNVAAYYQESGRAGRDGLQSYCRL 358

  Fly  1216 FLDAKGGDQSELRRHVYSNSIDRHVIR-------------KLLQKIFVPCSCDKEASKRTALPIP 1267
            :.   |.:.....|.:..|  |.|..|             |..:||       .|..:||.....
  Fly   359 YY---GREDVRSIRFLLQN--DAHRARGRGDKELLTERAIKQFEKI-------TEFCERTTCRHK 411

  Fly  1268 LEGD--GPRVHMCPGHEIGFSVEKTVEMLDIPAENISTLLCYMELDPRWCISVLSSAYVMAK--- 1327
            |..|  |.....|.|.         .::...|.:....|    |:..|.|:.....:::..:
  Fly   412 LFSDFFGDPTPDCSGQ---------CDVCKRPKKAEKAL----EIFHRLCMDDAFKSHISLQDCA 463

  Fly  1328 VISYGGPKYLKHAAKE 1343
            .:..||...:|.||:|
  Fly   464 DLYEGGRPGIKRAAQE 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RecQ4	NP_652607.1	RecQL4_SLD2_NTD	9..55	CDD:412085
		RecQ	855..>1216	CDD:440280	129/389 (33%)
RecQ5	NP_729983.1	RecQ	5..447	CDD:440280	150/502 (30%)
		SMC_N	658..>963	CDD:481474