Protein Alignment RecQ4 and hrq1

DIOPT Version :10

• Sequence 1: NP_652607.1
• Gene: RecQ4 / 53438
• FlyBaseID: FBgn0040290
• Length: 1579
• Species: Drosophila melanogaster
• Sequence 2: NP_594448.2
• Gene: hrq1 / 2542036
• PomBaseID: SPAC23A1.19C
• Length: 1063
• Species: Schizosaccharomyces pombe
• Alignment Length: 799
• Identity: 153/799 - (19%)
• Similarity: 260/799 - (32%)
• Gaps: 257/799 - (32%)

  Fly   741 NAAILQGDELNESEE--------DDQESSGDEEVQQHPDPNWSSDEMDVDFEALDAAVEASLSQP 797
            |..:..|..:::|.|        :.||.|.....::.|....:.....:||..|..|:|
pombe   136 NPELYTGSTVSQSSEYVLVIELLETQERSSKRRRREGPTMKANIQRQKLDFNNLKKAIE------ 194

  Fly   798 VSQEKAASPIKTYV---------------------------GHKIPEEFLKQAGLDTTASS---- 831
            :..:|....||.|:                           ...||.:.::...|:|.|.|
pombe   195 LRNQKFLQGIKEYIKKCQLTELDPTQQLLTQSRKNQPVPPDSPSIPNDSIENCNLNTKACSIEEL 259

  Fly   832 -----SNRSQHG-----------GVKPLYDLLPDGSVQDTTPEVLEALHMFGHTNFR---KGQDR 877
                 |..|..|           .|:..|..|.    :..:.|::.||  :...|..   |.|..
pombe   260 LNEIASESSYEGQIVQEALHTYPAVEAQYGALS----RPLSQELINAL--YTSRNIEKTYKHQAD 318

  Fly   878 AIMRTLSGLSSLVTLSTGSGKSLCYQLP---AYLYSRKVGAITLVISPLVSLMEDQVTGVPHFLR 939
            ||....:|...:|:.||.|||||.||:|   :.|...:  :....:.|..||.:||...:...|
pombe   319 AINHLWNGFHVIVSTSTSSGKSLIYQIPILQSLLEDNQ--STAFFVFPTKSLAQDQKKSLIDIL- 380

  Fly   940 AHCLHTNQTAPQRMKIQQMIANGEIDILLVSPEAVVAGERATGFGAILRQLPPIAFACIDEAH-- 1002
                   ...|....|:....:|  |..|.|.|:::....             |.|...|..|
pombe   381 -------SYMPTLKNIRVDTFDG--DTPLESRESIIRSAN-------------IIFTNPDMLHQT 423

  Fly  1003 ---CVSQWSHNFRPSYLMICK---------------VLRKNLGVRTVLG------LTATATLP-- 1041
               ..::|.:.|:...|.:..               |||:...:....|      ::.:||:.
pombe   424 ILPNANRWYYFFKNLKLFVLDEAHVYNGIFGVHVAFVLRRMRRIAEYFGNSQYRFVSCSATIEDP 488

  Fly  1042 ----------TRVSIINHLGISDGERGIIS------DIPLPDNLVLSVSKDENRDAALLQLLNSE 1090
                      ..:.:||:.....|.:..:.      |...||:...|...:.::   ||.....:
pombe   489 LQHMKKIFGVDNIKLINYTSSPSGSKKFVMWNPPYVDPKHPDDGKKSAISEASK---LLIKFAEK 550

  Fly  1091 RFEPCQSIIIYCTRRDECERIAGFIRTCVQDRREPTQDQTKKRKRVNWQAEPYHAGMPASRRRTV 1155
            |..    .|::|..|..||.:...:|         .:.:||::..:..:.:.|.||.....||.:
pombe   551 RVR----TIVFCRVRKTCESLMRLVR---------QELKTKQKGDLLSKIQSYRAGYTVQERRKI 602

  Fly  1156 QKAFMSNELRIVVATIAFGMGINKPDIRAVIHYNMPRNFESYVQEIGRAGRDGLPSHCHLFLDAK 1220
            :....:.:|..::||.|..:||:...:.|||....|.:..:..|:.|||||....|.....::..
pombe   603 ESEMFNGKLYGIIATNALELGIDIGSLDAVITIGFPYSLSNLRQQFGRAGRRNKSSLAVYIVETF 667

  Fly  1221 GGDQSELRR----HVYSNS-IDRHVIRKLLQKIFVPCSCDKEASKRTALPIPLEGDGPRVHMCPG 1280
            ..||..|:.    |...|: :...:..::|....:.|:..:       |||.:..|    ....|
pombe   668 PVDQFYLKHPILIHTQPNAELTLDLTNEVLLASHLQCAAYE-------LPINIRSD----EKFFG 721

  Fly  1281 HEIGFSVEKTVEMLDIPAENISTLLCYMELDPRWCISVLSSAYVMAKVISY-GGPKYLKHAAKEC 1344
            ::|....|..:||::                                 .|| ..||||...|.
pombe   722 NQIQDICEANLEMVE---------------------------------ESYRPHPKYLPFPAS-- 751

  Fly  1345 PPLAMAIALQIRDKTFKEDSNIIEFSVTDI---------------AAGIGWNSGVVKYQLK---- 1390
                     |:|.::..||.    |::.|:               .|...:...|..||.|
pombe   752 ---------QVRIRSVSEDM----FTLVDVTNDKNVILELLEPFRVALTAYEGAVYVYQGKTFII 803

  Fly  1391 ---------------DLEW 1394
                           |:||
pombe   804 RLLNINKRIITAHQVDVEW 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RecQ4	NP_652607.1	RecQL4_SLD2_NTD	9..55	CDD:412085
		RecQ	855..>1216	CDD:440280	87/410 (21%)
hrq1	NP_594448.2	CDT1	51..222	CDD:215014	17/91 (19%)
		YprA	255..1035	CDD:440818	131/674 (19%)