DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RecQ4 and Recql5

DIOPT Version :9

Sequence 1:	NP_652607.1	Gene:	RecQ4 / 53438	FlyBaseID:	FBgn0040290	Length:	1579	Species:	Drosophila melanogaster
Sequence 2:	XP_006532421.1	Gene:	Recql5 / 170472	MGIID:	2156841	Length:	983	Species:	Mus musculus

Alignment Length:	415	Identity:	136/415 - (32%)
Similarity:	207/415 - (49%)	Gaps:	85/415 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   865 MFGHTNFRKG-QDRAIMRTLSGLSSL-VTLSTGSGKSLCYQLPAYLYSRKVGAITLVISPLVSLM 927
            :||..:|:.. |:.|.|..:.|...: |.:.||:||||||||||.|.|    .||:|:|||::|:
Mouse    24 VFGFDSFKTPLQESATMAVVKGAEDVFVCMPTGAGKSLCYQLPALLAS----GITIVVSPLIALI 84

  Fly   928 EDQVTGVPHFL----RAHCLHTNQTAPQRMKIQQMIANGEID-----ILLVSPE-AVVAGERATG 982
            :||   |.|.|    :...|::..:..:|   ::::::.|.|     :|.::|| |..|..:.|.
Mouse    85 QDQ---VDHLLALKVQVSSLNSKLSVQER---KELLSDLERDKPRTKLLYITPEMAASASFQPTL 143

  Fly   983 FGAILRQLPPIAFACIDEAHCVSQWSHNFRPSYLMICKVLRKNLGVRTVLGLTATATLPTRVSII 1047
            ...:.|.|  :::..:|||||||||.|:|||.||.: ..||..|.....:.||||||...:..:.
Mouse   144 NSLVSRNL--LSYLVVDEAHCVSQWGHDFRPDYLRL-GALRSRLAHAPCVALTATATPQVQEDVF 205

  Fly  1048 NHLGISDG---------ERGIISDIP----LPD---NLVLSVSKDENRDAALLQLLNSERFEPCQ 1096
            ..|.:...         ...:..|:.    :||   ||         ||..|..|  .::.|...
Mouse   206 AALHLKQPVASFKTPCFRANLFYDVQFKELIPDVYGNL---------RDFCLKAL--GQKAENGS 259

  Fly  1097 SI---IIYCTRRDECERIAGFIRTCVQDRREPTQDQTKKRKRVNWQAEPYHAGMPASRRRTVQKA 1158
            |.   |:||..|:.||::|..:.:                :.||  |:.||||:.||.|..||..
Mouse   260 SSGCGIVYCRTREACEQLAIELSS----------------RGVN--AKAYHAGLKASDRTQVQNE 306

  Fly  1159 FMSNELRIVVATIAFGMGINKPDIRAVIHYNMPRNFESYVQEIGRAGRDGLPSHCHLFLDAKGGD 1223
            :|..::.::||||:||||::|.::|.|.|:|:.::...|.||.|||||||.||.|.|:......|
Mouse   307 WMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRD 371

  Fly  1224 QSELRRHVYSNSIDRHVIRKLLQKI 1248
            |...            :|||.|.|:
Mouse   372 QVSF------------LIRKELAKL 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RecQ4	NP_652607.1	RecQL4_SLD2_NTD	9..55	CDD:421279
RecQ4	NP_652607.1	RecQ	864..>1218	CDD:223588	129/383 (34%)
Recql5	XP_006532421.1	RecQ	16..>440	CDD:223588	136/415 (33%)
Recql5	XP_006532421.1	RecQ5	627..815	CDD:311110
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0514
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D445763at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820