DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sulf1 and Arsg

DIOPT Version :9

Sequence 1:	NP_001262626.1	Gene:	Sulf1 / 53437	FlyBaseID:	FBgn0040271	Length:	1114	Species:	Drosophila melanogaster
Sequence 2:	NP_001348904.1	Gene:	Arsg / 74008	MGIID:	1921258	Length:	525	Species:	Mus musculus

Alignment Length:	432	Identity:	93/432 - (21%)
Similarity:	155/432 - (35%)	Gaps:	131/432 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 SNSARERRPNIILILTDDQD-VELGSLNFM----PRTLRLLRDGGAEFRHAYTTTPMCCPARSSL 105
            |...|..:|||::||.||.. .:||: |:.    ...|..:...|..|...:.....|.|:|:||
Mouse    28 SGKTRAPQPNIVIILADDMGWGDLGA-NWAETKDTTNLDKMASEGMRFVDFHAAASTCSPSRASL 91

  Fly   106 LTG-MYVHNHMVFTNNDNCSSPQWQATHETRSYATYLSNAGYRTGYFGKYLNKYNGSYIP----- 164
            ||| :.:.|.:  |:|...:|......:|| :.|..|...||.|...||:...::|||.|
Mouse    92 LTGRLGLRNGV--THNFAVTSVGGLPVNET-TLAEVLRQEGYVTAMIGKWHLGHHGSYHPNFRGF 153

  Fly   165 -----------------PG---------------WREWG---------GLIMNSKYYNYSINLNG 188
                             ||               ||..|         .|..|.......:||:|
Mouse   154 DYYFGIPYSNDMGCTDAPGYNYPPCPACPQRDGLWRNPGRDCYTDVALPLYENLNIVEQPVNLSG 218

  Fly   189 QKIKHGFDYAKDYYPDLIANDSIAFLRSSKQQNQRKPVLLTMSFPAPHGPEDSAPQYSHLFFNVT 253
            ...|:             |..::.|:..:....  :|.||.:.....|.|....|..:|
Mouse   219 LAQKY-------------AERAVEFIEQASTSG--RPFLLYVGLAHMHVPLSVTPPLAH------ 262

  Fly   254 THHTPSYDHAPNPDKQWILRVTEPMQPVHKRFTNLLMTKRLQTLQSVDVAVERVYNELKELGELD 318
                        |.:|.:.|.                     :|:.:|..|.::.:::..:.. :
Mouse   263 ------------PQRQSLYRA---------------------SLREMDSLVGQIKDKVDHVAR-E 293

  Fly   319 NTYIVYTSDHG---------YHLGQF--------GLIKGKSFPFEFDVRVPFLIRGPGIQASKVV 366
            ||.:.:|.|:|         ..:|.|        |....|...:|...|||.|...||...:.|.
Mouse   294 NTLLWFTGDNGPWAQKCELAGSVGPFFGLWQTHQGGSPTKQTTWEGGHRVPALAYWPGRVPANVT 358

  Fly   367 NEIVLN-VDLAPTFLDMGG--VPTPQHMDGRSILPLLLSRNR 405
            :..:|: :|:.||.:.:.|  :|..:..|||.:..:|..:::
Mouse   359 STALLSLLDIFPTVIALAGASLPPNRKFDGRDVSEVLFGKSQ 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sulf1	NP_001262626.1	AslA	51..>398	CDD:225661	90/418 (22%)
		G6S	53..408	CDD:293766	91/425 (21%)
		DUF3740	640..790	CDD:289325
		ALP_like	<940..989	CDD:304875
Arsg	NP_001348904.1	ARSG	35..469	CDD:293780	91/425 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810