DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sulf1 and arsg

DIOPT Version :9

Sequence 1:	NP_001262626.1	Gene:	Sulf1 / 53437	FlyBaseID:	FBgn0040271	Length:	1114	Species:	Drosophila melanogaster
Sequence 2:	NP_001352290.1	Gene:	arsg / 564790	ZFINID:	ZDB-GENE-060503-154	Length:	526	Species:	Danio rerio

Alignment Length:	561	Identity:	130/561 - (23%)
Similarity:	208/561 - (37%)	Gaps:	147/561 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IGGLILLLFVLNVFSKEQGSHSHKRSHSAKRFSRDSNSARERRPNIILILTDDQDVELGSL---- 71
            :|...||:|        .|...|.:||    ..::.|...:.|||.|:||.|  |:..|.|
Zfish     4 LGFCTLLVF--------SGLLHHIKSH----IKKEDNPEGKERPNFIIILAD--DIGWGDLWLNR 54

  Fly    72 --NFMPRT-LRLLRDGGAEFRHAYTTTPMCCPARSSLLTGMYVHNHMVFTNNDNCSSPQWQATHE 133
              |..|.. |..|...|..|...::....|.|:|:|:|||.:...:.| |:|....|......:|
Zfish    55 PDNSTPTPWLDSLMLKGKRFTDFHSPASTCSPSRASILTGRHGLRNGV-THNFAVGSVGGLPLNE 118

  Fly   134 TRSYATYLSNAGYRTGYFGKYLNKYNGSYIP-----------PGWREWG-----GLIMNS----K 178
            | ::|..|.:.||.|...||:...:||||.|           |...:.|     ||.:.|    .
Zfish   119 T-TFAQLLHDEGYYTAMIGKWHLGHNGSYSPVHRGFDYYLGIPYSNDMGCTDKPGLDLPSCPPCV 182

  Fly   179 YYNYSINLNGQKIKHGFDYAKDYYPDLIANDSI------------AFLRSSKQQ------NQRKP 225
            :..||||.     ||...|.|...| |..|:.|            .:..::.||      .:::|
Zfish   183 HSQYSINK-----KHEGCYTKVGLP-LFENEKIIEQPLDTWSLKDRYATAAVQQIFTASVTKKQP 241

  Fly   226 VLLTMSFPAPHGPEDSAPQYSHLFFNVTTHHTPSYDHAPNPDKQWILRVTEPMQPVHKRFTNLLM 290
            .||.::....|     .|.:.:.|.||||.                    :|            .
Zfish   242 FLLYVALAHMH-----VPLFHNTFLNVTTE--------------------DP------------Y 269

  Fly   291 TKRLQTLQS-VDVAVERVYNELKELGELDNTYIVYTSDHG---------YHLGQF--------GL 337
            |..|..:.| |...|:.:..|     :|:||.|.:|.|:|         .|:|.|        |.
Zfish   270 TASLSDMDSLVGNIVQALITE-----QLENTLIWFTGDNGPWEQKCLFAGHVGPFVGRWQTNKGG 329

  Fly   338 IKGKSFPFEFDVRVPFLIRGP-GIQASKVVNEIVLNVDLAPTFLDMGGV--PTPQHMDGRSILPL 399
            ...|...:|...|||.::..| .|:.:...:.::..:|:.||.|.:.||  |:.:..||..|..:
Zfish   330 GSAKRTTWEGGHRVPTVVSWPKKIKHNSSSDALLSGLDIFPTVLSLAGVKPPSDRRYDGIDITDV 394

  Fly   400 LLSRNRAVRDNWPDSFLIESSG-------------RRETAEQIAESRARLQIERRNMKLANSSLL 451
            ||:.:    :...:|.:..:||             :...|..|.........|....:..:..|:
Zfish   395 LLNDS----ETGHESLMHPNSGAAGQYGDLQTVRLKHHKAFYITGGSVACDGESGPQQHHDPPLI 455

  Fly   452 EDFLEGAGESTTIVSSSSTAATLMSSTAQQPEDGEEEVETD 492
            .|..:...|.|.:...|....:::....::.|....::.||
Zfish   456 FDLSQDEAEETPLDPESKEFRSVLKQVEREREALLWDIATD 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sulf1	NP_001262626.1	AslA	51..>398	CDD:225661	105/412 (25%)
		G6S	53..408	CDD:293766	107/420 (25%)
		DUF3740	640..790	CDD:289325
		ALP_like	<940..989	CDD:304875
arsg	NP_001352290.1	ALP_like	34..469	CDD:329031	117/490 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910