DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sulf1 and sgsh

DIOPT Version :9

Sequence 1:	NP_001262626.1	Gene:	Sulf1 / 53437	FlyBaseID:	FBgn0040271	Length:	1114	Species:	Drosophila melanogaster
Sequence 2:	NP_001116740.1	Gene:	sgsh / 563849	ZFINID:	ZDB-GENE-030131-4958	Length:	511	Species:	Danio rerio

Alignment Length:	417	Identity:	96/417 - (23%)
Similarity:	158/417 - (37%)	Gaps:	100/417 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 DSNSARERRPNIILILTDDQDVELGSLN---FMPRTLRLLRDGGAEFRHAYTTTPMCCPARSSLL 106
            |....|.|  |::||:.||...|....|   .....||.|......|::|:|:...|.|:||::|
Zfish    17 DVGGCRSR--NVLLIIADDGGFETDVYNNTVVQTPHLRALSKRSLIFKNAFTSVSSCSPSRSTIL 79

  Fly   107 TGMYVHNHMVFTNNDNCSSPQWQATHETRSY------ATYLSNAGYRTGYFGKYLNKYNGSYIPP 165
            ||:..|.:.::..:        |..|...|:      ...|..|...||..||       .::.|
Zfish    80 TGLPQHQNGMYGLH--------QGVHHFNSFDGVQSLPLLLKRANIHTGIIGK-------KHVGP 129

  Fly   166 GWREWGGLIMNSKYYNYSINLNGQKIKHGFDYAKDYYPDLIANDSIA--------FLRSSKQQ-- 220
            |           ..|.:.           |.|.::....|....:|.        |.:|.|::
Zfish   130 G-----------PVYPFD-----------FAYTEETNSVLQVGRNITKIKLLVRKFFQSHKEERS 172

  Fly   221 --NQRKPVLLTMSFPAPHGPEDSAPQYS---HLFFNVTTHHTPSYDHAP---NPDK----QWILR 273
              .:.:|..|.::|..||....|.|||.   ..|.|..:......|..|   :||:    .:|..
Zfish   173 ETKEERPFFLYVAFHDPHRCGHSQPQYGVFCEKFGNGESGMGRIPDWEPKYYSPDQVKVPYFIPD 237

  Fly   274 VTEPMQPVHKRFTNLLMTKRLQTLQSVDVAVERVYNELKELGELDNTYIVYTSDHGYHLGQFGLI 338
            .......:..::|         |:..:|..:..|..||::.|..::|.::|:||:|     ....
Zfish   238 TPAARADIAAQYT---------TVSRLDQGIGLVLEELRKAGFENDTLVIYSSDNG-----IPFP 288

  Fly   339 KGKSFPFEFDVRVPFLIRGPGIQA--SKVVNEIVLNVDLAPTFLDMGGVPTPQH---------MD 392
            .|::..:...|:.|.|:..|..|.  .|:....|..:|:.||.||...:|.|.:         :.
Zfish   289 NGRTNLYGSGVKEPMLLSSPEHQQRWGKLSQAYVSLLDITPTILDWFSLPYPSYSLSMSQPVELT 353

  Fly   393 GRSILPLLLSRNRAVRDNWPDSFLIES 419
            |||:||.|:|     ..:|...|..:|
Zfish   354 GRSLLPALIS-----EPSWDTVFSSQS 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sulf1	NP_001262626.1	AslA	51..>398	CDD:225661	87/388 (22%)
		G6S	53..408	CDD:293766	90/396 (23%)
		DUF3740	640..790	CDD:289325
		ALP_like	<940..989	CDD:304875
sgsh	NP_001116740.1	SGSH	25..481	CDD:293751	93/407 (23%)
sgsh	NP_001116740.1	AslA	25..461	CDD:225661	93/407 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810