DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sulf1 and arsk

DIOPT Version :9

Sequence 1:	NP_001262626.1	Gene:	Sulf1 / 53437	FlyBaseID:	FBgn0040271	Length:	1114	Species:	Drosophila melanogaster
Sequence 2:	NP_001070625.1	Gene:	arsk / 562412	ZFINID:	ZDB-GENE-060929-332	Length:	523	Species:	Danio rerio

Alignment Length:	427	Identity:	104/427 - (24%)
Similarity:	186/427 - (43%)	Gaps:	93/427 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ILLLFVLNVFSKEQGSHSHKRSHSAKRFSRDSNSARERRPNIILILTDDQDVELGSLNFMPRT-- 77
            :||:|.:|.:.......||.                  ||||::|::|..|   |.|.|.|..
Zfish     6 VLLIFNVNAYCMYLNWTSHD------------------RPNIVMIMSDAFD---GRLTFQPGNKV 49

  Fly    78 -----LRLLRDGGAEFRHAYTTTPMCCPARSSLLTGMYVHNHMVFTNNDNCSSPQWQATHETRSY 137
                 :..:|:.|:.|.::||.:|:|||:|:::.:|.:||....: ||:.|..|  .||    ::
Zfish    50 VQLPYINYMRELGSVFLNSYTNSPICCPSRAAMWSGQFVHLTQSW-NNNKCLHP--NAT----TW 107

  Fly   138 ATYLSNAGYRTGYFGKYLNKYNGSY-IPPGWREWGGLIMNSKYYNYSINLNGQKIKHGFDYA--- 198
            ...|..:||.|...|| |:..:|.: :......|      ::...:.:...|:.:......|
Zfish   108 MDDLRKSGYHTHSMGK-LDYTSGHHSVSNRVEAW------TRDVPFLLRQEGRPVTDLVGDASTK 165

  Fly   199 ----KDYYPDLIANDSIAFLRSSKQQ-NQRKPVLLTMSFPAPHGPEDSAPQYSHLFFNVTTH--H 256
                ||:   .|.:.::.::|::... .|...:.|.::.|.|:..:...|......|..:.:  :
Zfish   166 RVMIKDW---TITDAAVQWIRNTTASLTQPFALYLGLNLPHPYRTDSLGPTAGGSTFRTSPYWLN 227

  Fly   257 TPSYDHAPNPDKQWILRVTEPMQPVH------KRFTNLLMTKRLQTLQS--------VDVAVERV 307
            ..||:....|  :| ||..: |.||.      |..:.....:.::.:::        .|..:..|
Zfish   228 KVSYNQVSVP--KW-LRFKD-MHPVDYYSTVTKNCSGHFTEEEIRNIRAFYYAMCAETDGMLGEV 288

  Fly   308 YNELKELGELDNTYIVYTSDHG---------YHLGQFGLIKGKSFPFEFDVRVPFLIRGPGIQAS 363
            ...|::.|.|:.|.:::|||||         |.:..|   :|.|       .||.||.|||:::.
Zfish   289 MAALRDTGSLNKTVVLFTSDHGDLAMEHRQFYKMSMF---EGSS-------HVPLLIMGPGVKSG 343

  Fly   364 KVVNEIVLNVDLAPTFLDMGGVPTPQHMDGRSILPLL 400
            ..|:..|..||:.||.||:.|||....:.|.|::||:
Zfish   344 FEVSLPVSLVDIYPTVLDLAGVPQTGGLSGHSLIPLI 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sulf1	NP_001262626.1	AslA	51..>398	CDD:225661	96/387 (25%)
		G6S	53..408	CDD:293766	98/389 (25%)
		DUF3740	640..790	CDD:289325
		ALP_like	<940..989	CDD:304875
arsk	NP_001070625.1	AslA	25..445	CDD:225661	98/408 (24%)
arsk	NP_001070625.1	ARSK	27..439	CDD:293781	97/388 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592927
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740