Protein Alignment Sulf1 and STS

DIOPT Version :9

• Sequence 1: NP_001262626.1
• Gene: Sulf1 / 53437
• FlyBaseID: FBgn0040271
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: NP_001307679.1
• Gene: STS / 412
• HGNCID: 11425
• Length: 590
• Species: Homo sapiens
• Alignment Length: 506
• Identity: 122/506 - (24%)
• Similarity: 187/506 - (36%)
• Gaps: 166/506 - (32%)

  Fly     2 MRHSSLRLIIGGL---ILLLFVLNVFSKEQGSHSHKRSHSAKRFSRDSNSARERRPNIILILTDD 63
            |....|:|.|..:   .||||.|          ....||:|.            ||||||::.||
Human     1 MAQDRLQLFIAKMKIPFLLLFFL----------WEAESHAAS------------RPNIILVMADD 43

  Fly    64 QDVE----LGSLNFMPRTLRLLRDGGAEFRHAYTTTPMCCPARSSLLTGMY-VHNHM-------- 115
            ..:.    .|:.......:..|..||.:.......:|:|.|:|::.:||.| |.:.|
Human    44 LGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGV 108

  Fly   116 -VFTNNDNCSSPQWQATHETRSYATYLSNAGYRTGYFGKYLNKYNGSYIPPGWREWG-GLIMNSK 178
             :||     :|.....|.|. ::|..|.:.||.|...||                |. |:..:||
Human   109 FLFT-----ASSGGLPTDEI-TFAKLLKDQGYSTALIGK----------------WHLGMSCHSK 151

  Fly   179 YYNYSINLNGQKIKHGFDYAKDYYPDLIANDSIAFLRSSKQQNQRKP------------------ 225
                 .:.....:.|||:|   :|...:.|     ||..      ||
Human   152 -----TDFCHHPLHHGFNY---FYGISLTN-----LRDC------KPGEGSVFTTGFKRLVFLPL 197

  Fly   226 -----VLLTMS-------FPAPHGPEDS----APQYSHLFFNVTTHHTP---------------- 258
                 .|||::       ...|.|...|    |.....||.....:..|
Human   198 QIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPLNCFMMRNYEIIQQPM 262

  Fly   259 SYDHAPN----PDKQWILRVTEP-----MQPVHKRFTNLLMTKRL----------QTLQSVDVAV 304
            |||:...    ...|:|.|.||.     :..:|.. |.|..:|..          ..::.:|.:|
Human   263 SYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVH-TALFSSKDFAGKSQHGVYGDAVEEMDWSV 326

  Fly   305 ERVYNELKELGELDNTYIVYTSDHGYHL-----------GQFGLIK-GKSFPFEFDVRVPFLIRG 357
            .::.|.|.||...::|.|.:|||.|.|:           |..|:.| ||:..:|..:|||.::|.
Human   327 GQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGKANNWEGGIRVPGILRW 391

  Fly   358 PG-IQASKVVNEIVLNVDLAPTFLDMGGVPTPQH--MDGRSILPLLLSRNR 405
            |. |||.:.::|...|:|:.||...:.|.|.|:.  :|||.::|||..:::
Human   392 PRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRIIDGRDLMPLLEGKSQ 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sulf1	NP_001262626.1	AslA	51..>398	CDD:225661	107/445 (24%)
		G6S	53..408	CDD:293766	110/452 (24%)
		DUF3740	640..790	CDD:289325
		ALP_like	<940..989	CDD:304875
STS	NP_001307679.1	AslA	30..555	CDD:225661	111/467 (24%)
		ES	33..557	CDD:293778	110/452 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157212
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740