DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sulf1 and Ids

DIOPT Version :9

Sequence 1:	NP_001262626.1	Gene:	Sulf1 / 53437	FlyBaseID:	FBgn0040271	Length:	1114	Species:	Drosophila melanogaster
Sequence 2:	NP_647814.1	Gene:	Ids / 38423	FlyBaseID:	FBgn0035445	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	113/466 - (24%)
Similarity:	185/466 - (39%)	Gaps:	95/466 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 SARERRPNIILILTDDQDVELG----SLNFMPRTLRLLRDGGAEFRHAYTTTPMCCPARSSLLTG 108
            :|..||||:::::.||....:|    :|...|......| |...|...|:...:|.|:|:|||||
  Fly    19 AAPPRRPNVVMVIFDDLRPVIGAYGDTLASTPYLDNFAR-GSHIFTRVYSQQSLCAPSRNSLLTG 82

  Fly   109 -----MYVHNH----MVFTNNDNCSSPQWQATHETRSYATYLSNAGYRTGYFGKYLNKYNGSYIP 164
                 :::::.    ..||.|.. :.||:...|   .|.||.....:..|......:.|..|:..
  Fly    83 RRPDTLHLYDFYSYWRTFTGNFT-TLPQYFKEH---GYYTYSCGKVFHPGLSSNNTDDYPLSWSA 143

  Fly   165 PGWREWGGLIMNS-----------KYYNYSINLNGQKIKHGFDYAKDYYPDLIANDSIA-FLR-- 215
            |.:|......|||           |.....:.|..|..|        ..||:   :|:| .||
  Fly   144 PAFRPRTEQFMNSPVCPDKEGILRKNLICPVELQTQPYK--------TLPDI---ESVAEALRFV 197

  Fly   216 SSKQQNQRKPVLLTMSFPAPHGPEDSAPQYSHLFFNVTTHHTPSYDHAPNPDK---QWILRVTEP 277
            .|:.::.::|..|.|.|..|| .....|:.....||::..:..:.|....||.   .|     .|
  Fly   198 GSRSRHSQEPFFLAMGFHKPH-INFRFPRQFLSRFNLSQFYNYTEDSLKPPDMPAVAW-----NP 256

  Fly   278 MQPVHKR-----------FTNLLMTKRLQTLQSVDVAVERVYNEL--KELG--ELDNTYIVYTSD 327
            ...|..|           :..:...:..|..||...:|..| ::|  |.:|  :||.|.:|...|
  Fly   257 YTDVRARDDFKHSNISFPYGPISPLQAAQIRQSYYASVSYV-DDLFGKLIGGLDLDETVVVALGD 320

  Fly   328 HGYHLGQFGLIKGKSFPFEFDVRVPFLIRGP--GIQASKVVNEIVLNVDLAPTFLDMGGVP---- 386
            ||:.||:.. ...|...||..:|||.:||.|  .:..:|..:.|...:|:.||.:|:.|:|
  Fly   321 HGWSLGEHA-EWAKYSNFEVALRVPLIIRSPQFPVAQTKYYHGITELLDVFPTLVDLAGLPKLDK 384

  Fly   387 --TPQHM---DGRSILPLLLSRNRA----VRDNWPDSFLIESSGRRETAEQIAESRARLQIERRN 442
              :.|.:   :|:|:...|:...||    ....:|...::.:........::           ||
  Fly   385 CQSSQELTCGEGKSLYHQLMGLGRADEHVALSQYPRPGMLPTKHPNSDKPKL-----------RN 438

  Fly   443 MKLANSSLLED 453
            :|:...||..|
  Fly   439 IKIMGYSLRTD 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sulf1	NP_001262626.1	AslA	51..>398	CDD:225661	102/402 (25%)
		G6S	53..408	CDD:293766	104/414 (25%)
		DUF3740	640..790	CDD:289325
		ALP_like	<940..989	CDD:304875
Ids	NP_647814.1	AslA	21..509	CDD:225661	112/464 (24%)
Ids	NP_647814.1	iduronate-2-sulfatase	24..495	CDD:293754	111/461 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466513
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740