DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sulf1 and Arse

DIOPT Version :9

Sequence 1:	NP_001262626.1	Gene:	Sulf1 / 53437	FlyBaseID:	FBgn0040271	Length:	1114	Species:	Drosophila melanogaster
Sequence 2:	NP_001041350.1	Gene:	Arse / 310326	RGDID:	1304917	Length:	611	Species:	Rattus norvegicus

Alignment Length:	455	Identity:	93/455 - (20%)
Similarity:	160/455 - (35%)	Gaps:	152/455 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 RPNIILILTDDQDV-ELGSL-NFMPRTLRL--LRDGGAEFRHAYTTTPMCCPARSSLLTGMY-VH 112
            |||.::|:.||..: :||.. |...||..:  |.:.|...........:|.|:|::.|||.| :.
  Rat    34 RPNFLIIMADDLGIGDLGCYGNTSIRTPNIDRLAEDGVRLTQYLAAESVCTPSRAAFLTGRYPIR 98

  Fly   113 NHMVFTNNDNCSSPQWQA-----THETRSYATYLSNAGYRTGYFGKY----------------LN 156
            :.|  |:.:.....||.|     ..:..::|..|...||.||..||:                ||
  Rat    99 SGM--TSGNGHRVLQWAAGAGGLPPKEITFARILQGQGYVTGLVGKWHLGLSCRTVSDLCHHPLN 161

  Fly   157 -------------------------------KYNGS---------------------YIPPGWRE 169
                                           :..|:                     ..|..|..
  Rat   162 HGFHHFLGLPLGMMGDCAGAEPSEKRAGLERRLRGAGRALAAVAVAIAALAWGRGRGLAPACWAP 226

  Fly   170 W--------------GGLIMNSKYYNYSINLNGQKIKHGFDYAKDYYPDLIANDSIAFLRSSKQQ 220
            |              |..::......|...|.............|:...|:..::..|||    :
  Rat   227 WAAIALGAVAAIFEAGSYVVGGAVARYDCFLMRNATVTQQPLQLDHVTPLLLREAKDFLR----R 287

  Fly   221 NQRKPVLLTMSFPAPHGPEDSAPQYSHLFFNVTTHHTPSYDHAPNPDKQWILRVTEPMQPVHKRF 285
            ::..|.||.:|....|.|..::|::..                               :..|.|:
  Rat   288 HRHAPFLLFLSLLHTHTPLVTSPEFRG-------------------------------RSAHGRY 321

  Fly   286 TNLLMTKRLQTLQSVDVAVERVYNELKELGELDNTYIVYTSDHGYHL----------GQFGLIK- 339
            .:        .::.:|..|.::...|:..|..|:|.:.:|||:|..|          |..|:.:
  Rat   322 GD--------NVEEMDWVVGQILEVLEHEGLTDSTLVHFTSDNGAWLEAQAGGEQLGGSNGVFRG 378

  Fly   340 GKSF-PFEFDVRVPFLIRGPGI-QASKVVNEIVLNVDLAPTFLDMGG--VPTPQHMDGRSILPLL 400
            ||.. .:|..:|||.:.|.||: ...:|:::.|..:|:.||.:.:||  :|:.:.:|||.:||||
  Rat   379 GKGMGGWEGGIRVPGVFRWPGVLPRGRVLDQPVSLMDVFPTVVRLGGGVLPSDREIDGRDLLPLL 443

Fly 401 400
Rat 444 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sulf1	NP_001262626.1	AslA	51..>398	CDD:225661	89/451 (20%)
		G6S	53..408	CDD:293766	93/455 (20%)
		DUF3740	640..790	CDD:289325
		ALP_like	<940..989	CDD:304875
Arse	NP_001041350.1	AslA	31..541	CDD:225661	93/455 (20%)
Arse	NP_001041350.1	ALP_like	34..531	CDD:304875	93/455 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351120
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1273622at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750