DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sulf1 and Arsi

DIOPT Version :9

Sequence 1:	NP_001262626.1	Gene:	Sulf1 / 53437	FlyBaseID:	FBgn0040271	Length:	1114	Species:	Drosophila melanogaster
Sequence 2:	NP_001041346.1	Gene:	Arsi / 307404	RGDID:	1310242	Length:	573	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	102/393 - (25%)
Similarity:	158/393 - (40%)	Gaps:	83/393 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 NSARERRPNIILILTDDQ---DVELGSLNFMPRTLRLLRDGGAEFRHAYTTTPMCCPARSSLLTG 108
            ::|..:.|:||.||||||   ||.....:....||..|...|.:..: |...|:|.|:||.||||
  Rat    40 SAAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAEGVKLEN-YYIQPICTPSRSQLLTG 103

  Fly   109 MY-VH----NHMVFTNNDNCSSPQWQATHETRSYATYLSNAGYRTGYFGK-YLNKYNGSYIPP-- 165
            .| :|    :.::.....|| .|..|.|...:     |..|||.|...|| :|..|....:|.
  Rat   104 RYQIHTGLQHSIIRPRQPNC-LPLDQVTLPQK-----LQEAGYSTHMVGKWHLGFYRKECLPTRR 162

  Fly   166 GWREW-GGLIMNSKYYNYSINLNGQKIKHGFD----------YAKDYYPDLIANDSIAFLRSSKQ 219
            |:..: |.|..|..||.|. |.:|..: .|||          .:..|...|.|..:...|.|...
  Rat   163 GFDTFLGSLTGNVDYYTYD-NCDGPGV-CGFDLHEGESVAWGLSGQYSTMLYAQRASHILASHSP 225

  Fly   220 QNQRKPVLLTMSFPAPHGPEDSAPQYSHLFFNVTTHHTPSYDHAPNPDKQWILRVTEPMQPVHKR 284
            |   ||:.|.::|.|.|.|..|..:|.:.:                                 :.
  Rat   226 Q---KPLFLYVAFQAVHTPLQSPREYLYRY---------------------------------RT 254

  Fly   285 FTNLLMTKRLQTLQSVDVAVERVYNELKELGELDNTYIVYTSDHGYHLGQFGLIKGKSFP----- 344
            ..|:...|....:..:|.||..:...||..|..:|:.|:::||:|   || ....|.::|
  Rat   255 MGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNG---GQ-TFSGGSNWPLRGRK 315

  Fly   345 ---FEFDVRVPFLIRGPGIQASKVVNEIVLNV-DLAPTFLDMGGVPT--PQHMDGRSILPLLLSR 403
               :|..||....:..|.::..:..:..:::: |..||.:.:.|..|  ...:||..:.| .:|.
  Rat   316 GTYWEGGVRGLGFVHSPLLKKKRRTSRALVHITDWYPTLVGLAGGTTSAADGLDGYDVWP-AISE 379

  Fly   404 NRA 406
            .||
  Rat   380 GRA 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sulf1	NP_001262626.1	AslA	51..>398	CDD:225661	97/379 (26%)
		G6S	53..408	CDD:293766	101/387 (26%)
		DUF3740	640..790	CDD:289325
		ALP_like	<940..989	CDD:304875
Arsi	NP_001041346.1	4-S	48..478	CDD:293753	100/385 (26%)
		AslA	49..485	CDD:225661	100/384 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	506..550
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351114
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740