DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sulf1 and Galns

DIOPT Version :9

Sequence 1:	NP_001262626.1	Gene:	Sulf1 / 53437	FlyBaseID:	FBgn0040271	Length:	1114	Species:	Drosophila melanogaster
Sequence 2:	XP_017456734.1	Gene:	Galns / 292073	RGDID:	1565391	Length:	567	Species:	Rattus norvegicus

Alignment Length:	462	Identity:	99/462 - (21%)
Similarity:	167/462 - (36%)	Gaps:	123/462 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 TTTPMCCP-----ARSSLLTGMYVHNHMVFTNN---DNCSSPQ---------------------- 127
            :..|..|.     :|::||||.....:..:|.|   .|..:||
  Rat   113 SAAPQHCATAHGRSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIMGGIPNSEHLLPELLKKAGY 177

  Fly   128 -------WQATHETRSYATYLSNA-----GYRTGYFGKYLNKYNGSYIPPGWREWGGLIMNSKYY 180
                   |...|..:.:.  |.:.     |....:||.|.||...:.  |.:|:|.   |..::|
  Rat   178 TNKIVGKWHLGHRPQFHP--LKHGFDEWFGSPNCHFGPYDNKVKPNI--PVYRDWE---MVGRFY 235

  Fly   181 -NYSINLNGQKIKHGFDYAKDYYPDLIANDSIAFLRSSKQQNQRKPVLLTMSFPAPHGPEDSAPQ 244
             .:.|||     |.|    :.....|...:::.|:|:  |..::.|..|..:..|.|     ||.
  Rat   236 EEFPINL-----KTG----EANLTQLYLQEALDFIRT--QHARQSPFFLYWAIDATH-----APV 284

  Fly   245 YSHLFFNVTTHHTPSYDHAPNPDKQWILRVTEPMQPVHKRFTNLLMTKRL-QTLQSVDVAVERVY 308
            |:                                   .|:|....:..|. ..::.:|.:|.::.
  Rat   285 YA-----------------------------------SKQFLGTSLRGRYGDAVREIDDSVGKIL 314

  Fly   309 NELKELGELDNTYIVYTSDHGYHL-------GQFG-LIKGKSFPFEFDVRVPFLIRGPG-IQASK 364
            :.|:.||...||::.:|||:|..|       |..| .:.||...||..:|.|.:...|| |.|.:
  Rat   315 SLLQNLGISKNTFVFFTSDNGAALISAPKEGGSNGPFLCGKQTTFEGGMREPAIAWWPGHIAAGQ 379

  Fly   365 VVNEIVLNVDLAPTFLDMGGV--PTPQHMDGRSILPLLLSRNRAVRDNWPDSFLIESSGRRETAE 427
            |.:::...:||..|.|.:.|:  |:.:.:||..:||.:|      :.:..|..:....|....|.
  Rat   380 VSHQLGSIMDLFTTSLSLAGLKPPSDRVIDGLDLLPTML------QGHIIDRPIFYYRGNTLMAV 438

  Fly   428 QIAESRARLQIERRNMKLANSSLLEDFLEGAGES--TTIVSSSSTAATLMSSTAQQPEDGEEEVE 490
            .:.:.:|.|.....:.:.....:  ||..|...|  ||......|...|:....:.|.:......
  Rat   439 TLGQYKAHLWTWTNSWEEFRQGI--DFCPGQNVSGVTTHTQEEHTELPLIFHLGRDPGERFPLRF 501

  Fly   491 TDNEEDD 497
            |.||..|
  Rat   502 TSNEYQD 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sulf1	NP_001262626.1	AslA	51..>398	CDD:225661	78/359 (22%)
		G6S	53..408	CDD:293766	81/369 (22%)
		DUF3740	640..790	CDD:289325
		ALP_like	<940..989	CDD:304875
Galns	XP_017456734.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810