Protein Alignment Sulf1 and ARSG

DIOPT Version :9

• Sequence 1: NP_001262626.1
• Gene: Sulf1 / 53437
• FlyBaseID: FBgn0040271
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: XP_011522838.1
• Gene: ARSG / 22901
• HGNCID: 24102
• Length: 552
• Species: Homo sapiens
• Alignment Length: 605
• Identity: 137/605 - (22%)
• Similarity: 207/605 - (34%)
• Gaps: 171/605 - (28%)

  Fly    46 SNSARERRPNIILILTDDQD-VELGSLNFM----PRTLRLLRDGGAEFRHAYTTTPMCCPARSSL 105
            |...|.::||.::||.||.. .:||: |:.    ...|..:...|..|...:.....|.|:|:||
Human    28 SGKTRGQKPNFVIILADDMGWGDLGA-NWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASL 91

  Fly   106 LTG-MYVHNHMVFTNNDNCSSPQWQATHETRSYATYLSNAGYRTGYFGKYLNKYNGSYIPPGWRE 169
            ||| :.:.|.:  |.|...:|......:|| :.|..|..|||.||..||:...::|||.|
Human    92 LTGRLGLRNGV--TRNFAVTSVGGLPLNET-TLAEVLQQAGYVTGIIGKWHLGHHGSYHP----- 148

  Fly   170 WGGLIMNSKYYNYSINLNGQKIKHGFDY--AKDYYPDLIANDSIAFLRSSKQQNQRKPVLLTMSF 232
                       |:          .||||  ...|..|:...|:..:         ..|
Human   149 -----------NF----------RGFDYYFGIPYSHDMGCTDTPGY---------NHP------- 176

  Fly   233 PAPHGPEDSAPQ-------YSH----LFFNVTTHHTP--------SY--------DHAPNPDKQW 270
            |.|..|:...|.       |:.    |:.|:.....|        .|        ..|....:.:
Human   177 PCPACPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPF 241

  Fly   271 ILRVTEPMQPVHKRFTNLLMTKRLQTLQ-----SVDVAV----ERVYNELKELGELDNTYIVYTS 326
            :|.|......|....|.|....|.::|.     .:|..|    ::|.:.:||     ||::.:|.
Human   242 LLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDHTVKE-----NTFLWFTG 301

  Fly   327 DHG---------YHLGQF--------GLIKGKSFPFEFDVRVPFLIRGPGIQASKVVNEIVLNV- 373
            |:|         ..:|.|        |....|...:|...|||.|...||.....|.:..:|:|
Human   302 DNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVL 366

  Fly   374 DLAPTFLDMGGVPTPQ--HMDGRSILPLLLSRNRAVRDNWPDSFLIESSGRRETAEQIAESRARL 436
            |:.||.:.:.....||  ..||..:..:|..|::              .|.||     .|:....
Human   367 DIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQ--------------PGHRE-----EEAGGGK 412

  Fly   437 QIERRNMKLANSSLLEDFL-------EGAGE--STTIVSSSSTAATLMSSTAQQPEDGEEEVETD 492
            :.|.....|.|:..:..||       ..|||  :...|......|..::..|:.. ||....|..
Human   413 EAEGAQSPLCNALQMHGFLVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARAC-DGSTGPELQ 476

  Fly   493 -------NEEDDVDGDGAMDSSAAALEEDDLD-DAAFEEGDEELDQEFQQ--NNDLPLAPYITKM 547
                   |.|||.       :.|..||....: .|...|..:.|....|.  |:::..|.|
Human   477 HKFPLIFNLEDDT-------AEAVPLERGGAEYQAVLPEVRKVLADVLQDIANDNISSADY---- 530

  Fly   548 MRLNSECSDPALLKNCLPGQ 567
                  ..||::...|.|.|
Human   531 ------TQDPSVTPCCNPYQ 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sulf1	NP_001262626.1	AslA	51..>398	CDD:225661	96/410 (23%)
		G6S	53..408	CDD:293766	98/418 (23%)
		DUF3740	640..790	CDD:289325
		ALP_like	<940..989	CDD:304875
ARSG	XP_011522838.1	ARSG	35..496	CDD:293780	121/538 (22%)
		AslA	35..457	CDD:225661	111/491 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810