Protein Alignment Sulf1 and sul-1

DIOPT Version :9

• Sequence 1: NP_001262626.1
• Gene: Sulf1 / 53437
• FlyBaseID: FBgn0040271
• Length: 1114
• Species: Drosophila melanogaster
• Sequence 2: NP_508560.1
• Gene: sul-1 / 180619
• WormBaseID: WBGene00006308
• Length: 709
• Species: Caenorhabditis elegans
• Alignment Length: 970
• Identity: 314/970 - (32%)
• Similarity: 431/970 - (44%)
• Gaps: 336/970 - (34%)

  Fly    55 NIILILTDDQDVELGSLNFMPRTLRLLRDGGAEFRHAYTTTPMCCPARSSLLTGMYVHNHMVFTN 119
            |:|||||||||:||||::|||:|.:::::.|.||...|.|||:|||:||::|||:|||||.|.||
 Worm    36 NVILILTDDQDIELGSMDFMPKTSQIMKERGTEFTSGYVTTPICCPSRSTILTGLYVHNHHVHTN 100

  Fly   120 NDNCSSPQWQATHETRSYATYLSNAGYRTGYFGKYLNKYNGSYIPPGWREWGGLIMNSKYYNYSI 184
            |.||:..:|:..||.:|...||..|||||.|.|||||:|:||||||||.||..::.|||:|||::
 Worm   101 NQNCTGVEWRKVHEKKSIGVYLQEAGYRTAYLGKYLNEYDGSYIPPGWDEWHAIVKNSKFYNYTM 165

  Fly   185 NLNGQKIKHGFDYAKDYYPDLIANDSIAFLRSSKQQNQRKPVLLTMSFPAPHGPEDSAPQYSHLF 249
            |.||::.|.|.:|.|||:.||:.|.|:.|:....:....:|..|.:|:||||||||.|||::|:|
 Worm   166 NSNGEREKFGSEYEKDYFTDLVTNRSLKFIDKHIKIRAWQPFALIISYPAPHGPEDPAPQFAHMF 230

  Fly   250 FNVTTHHTPSYDHAPNPDKQWILRVTEPMQPVHKRFTNLLMTKRLQTLQSVDVAVERVYNELKEL 314
            .|..:|.|.|::.||||||||:|:.|..|..||..||:||..:|||||||||..:||::|.|:||
 Worm   231 ENEISHRTGSWNFAPNPDKQWLLQRTGKMNDVHISFTDLLHRRRLQTLQSVDEGIERLFNLLREL 295

  Fly   315 GELDNTYIVYTSDHGYHLGQFGLIKGKSFPFEFDVRVPFLIRGPGIQASKVVNEIVLNVDLAPTF 379
            .:|.|||.:||||||||||||||:|||:.|:|||:||||.:|||||..:...||||.|||:|||.
 Worm   296 NQLWNTYAIYTSDHGYHLGQFGLLKGKNMPYEFDIRVPFFMRGPGIPRNVTFNEIVTNVDIAPTM 360

  Fly   380 LDMGGVPTPQHMDGRSILPLLLSRNRAVR-----DNWPDSFLIESSGRRETAEQIAESRARLQIE 439
            |.:.|||.|..|:|||:|.|:..:.:..:     ..|.|:.||| .|:....::|.:...:.:
 Worm   361 LHIAGVPKPARMNGRSLLELVALKKKKKKHMTALKPWRDTILIE-RGKMPKLKKIRDRYIKQK-- 422

  Fly   440 RRNMKLANSSLLEDFLEGAGESTTIVSSSSTAATLMSSTAQQPEDGEEEVETDNEEDDVDGDGAM 504
                                                                             
 Worm   423 ----------------------------------------------------------------- 422

  Fly   505 DSSAAALEEDDLDDAAFEEGDEELDQEFQQNNDLPLAPYITKMMRLNSECSDPALLKNCLPGQKW 569
                                     ::|.:.|            ||:.||......::|:.||.|
 Worm   423 -------------------------KKFNKEN------------RLSKECKRRKWQRDCVHGQLW 450

  Fly   570 KC-VNEEGRWRKHKCKFHLQLEHQLAAMPRKQYQRNCACFTPDGVVYTKIRAPSAGLHRVNKRTH 633
            || ...|.|||.:||              |..:...|:|
 Worm   451 KCYYTVEDRWRIYKC--------------RDNWSDQCSC-------------------------- 475

  Fly   634 NGPGRRRNKREVFHTELPDEMEELLDLHQVVDQLVDHTHRSKRDLPASSNETIAQVIQQIQSTLE 698
                  |.|||:.:.: .|:::|.|            |:..:.:
 Worm   476 ------RKKREISNYD-DDDIDEFL------------TYADREN--------------------- 500

  Fly   699 ILELKFNE-HELHASNSSGNSYERGEKYTKSGGHRCFVDATTAKVNCS-NVIYDDEKTWRTSRTQ 761
                 |:| ||.:    .|...:.||...:..|||. .....:|.:|| ||.:.
 Worm   501 -----FSEGHEWY----QGEFEDSGEVGEELDGHRS-KRGILSKCSCSRNVSHP----------- 544

  Fly   762 IDMLIKLLKDKIGKLKEMKKQLRESNKQALAAGRRNDNRRRNDQSVLDSGAGPEFNMSYFTEISS 826
                ||||:.|:.|...:|.:.:..|
 Worm   545 ----IKLLEQKMSKKHYLKYKKKPQN--------------------------------------- 566

  Fly   827 TPRSNVVGQTEVFQGYGSASAFDSLEQTQSHRFTPRAECYCEPDVGENHADSKEMAREARRKLKE 891
                            ||                                            ||
 Worm   567 ----------------GS--------------------------------------------LK- 570

  Fly   892 ERQRKKERKRIKKARLEKECLSEKMNCFSHDNQHWRTAPLWND--SPFCFCMNANNNTYSCLRTI 954
                            .|:|...:||||:|...||:|.|||.:  ..||||.|.|||||.||||.
 Worm   571 ----------------PKDCSLPQMNCFTHTASHWKTPPLWPEELGEFCFCQNCNNNTYWCLRTK 619

  Fly   955 NGTHNFLYCEFTTGLITFYNLTIDRFETINRAAGLTPGERSHMHDALDQLKSCRGRSCSI 1014
            |.|||||||||.|..|:||:...|..:.||....|..|....:.:.|..|:.|:.|.|.|
 Worm   620 NETHNFLYCEFVTEFISFYDFNTDPDQLINAVYSLDIGVLEQLSEQLRNLRKCKNRQCEI 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sulf1	NP_001262626.1	AslA	51..>398	CDD:225661	197/342 (58%)
		G6S	53..408	CDD:293766	199/352 (57%)
		DUF3740	640..790	CDD:289325	31/151 (21%)
		ALP_like	<940..989	CDD:304875	28/48 (58%)
sul-1	NP_508560.1	G6S	34..376	CDD:293766	195/339 (58%)
		AslA	36..>381	CDD:225661	198/344 (58%)
		ALP_like	<605..654	CDD:304875	28/48 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167718
Domainoid	1	1.000	430	1.000	Domainoid score	I300
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	611	1.000	Inparanoid score	I493
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46462
OrthoDB	1	1.010	-	-		D1273622at2759
OrthoFinder	1	1.000	-	-		FOG0001009
OrthoInspector	1	1.000	-	-		oto20521
orthoMCL	1	0.900	-	-		OOG6_104964
Panther	1	1.100	-	-	LDO	PTHR43108
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2825
SonicParanoid	1	1.000	-	-		X1396
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.800