DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sulf1 and gns

DIOPT Version :9

Sequence 1:	NP_001262626.1	Gene:	Sulf1 / 53437	FlyBaseID:	FBgn0040271	Length:	1114	Species:	Drosophila melanogaster
Sequence 2:	NP_001107314.1	Gene:	gns / 100135105	XenbaseID:	XB-GENE-978429	Length:	533	Species:	Xenopus tropicalis

Alignment Length:	386	Identity:	161/386 - (41%)
Similarity:	231/386 - (59%)	Gaps:	17/386 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 SNSARERRPNIILILTDDQDVELGSLNFMPRTLRLLRDGGAEFRHAYTTTPMCCPARSSLLTGMY 110
            |...|.|:||::|||||||||.||.:..:.:|..|:.|.|..|.:||..:.:|||:|||:|||.|
Frog    23 SVEGRSRKPNVVLILTDDQDVSLGGMTPLKKTKELIADHGMMFSNAYVASALCCPSRSSILTGRY 87

  Fly   111 VHNHMVFTN--NDNCSSPQWQATHETRSYATYLSNAGYRTGYFGKYLNKYNG------SYIPPGW 167
            .|||.|..|  ..||||..||.|.|..::...|.:.||:|.:.|||||:|..      :::||||
Frog    88 PHNHHVVNNTVEGNCSSKAWQKTQEPYTFPALLFSIGYQTFFAGKYLNQYGSEEAGGINHVPPGW 152

  Fly   168 REWGGLIMNSKYYNYSINLNGQKIKHGFDYAKDYYPDLIANDSIAFLRSSKQQNQRKPVLLTMSF 232
            ..|..|..|||||||:::.||:...||.:|::||..|::||.|:.||   ..::...|..:.::.
Frog   153 SYWFALEKNSKYYNYTLSENGRPKTHGENYSQDYLTDVLANVSLDFL---NYKSNYAPFFMMIAT 214

  Fly   233 PAPHGPEDSAPQYSHLFFNVTTHHTPSYDHAPNPDKQWILR-VTEPMQPVHKRFTNLLMTKRLQT 296
            ||||.|..:||||...|.||:.....:: :....||.|::| ...||.....::.:....||.||
Frog   215 PAPHSPWTAAPQYETAFLNVSAPRGSNF-NVHGKDKHWLIRQAKSPMSNSSIQYLDNAFQKRWQT 278

  Fly   297 LQSVDVAVERVYNELKELGELDNTYIVYTSDHGYHLGQFGLIKGKSFPFEFDVRVPFLIRGPGIQ 361
            |.|||..||::..:|:..||||||:|.:|||:|||.|||.|...|...:|||::||.|:|||||:
Frog   279 LLSVDDLVEKLVKQLEARGELDNTFIFFTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIK 343

  Fly   362 ASKVVNEIVLNVDLAPTFLDMGGVP-TPQHMDGRSILPLLLSRNRAVRDNWPDSFLIESSG 421
            .:::...:|.|:||.||.||:.|.. ....|||.|.||::::.:..   ||....|:|..|
Frog   344 PNQITKSLVANIDLGPTILDIAGYDLNKTQMDGMSFLPVMINNSNV---NWRTDILVEYQG 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sulf1	NP_001262626.1	AslA	51..>398	CDD:225661	152/356 (43%)
		G6S	53..408	CDD:293766	153/364 (42%)
		DUF3740	640..790	CDD:289325
		ALP_like	<940..989	CDD:304875
gns	NP_001107314.1	G6S	30..478	CDD:293766	158/379 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1273622at2759
OrthoFinder	1	1.000	-	-		FOG0001009
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010