Protein Alignment c11.1 and Mroh2a

DIOPT Version :9

• Sequence 1: NP_001285050.1
• Gene: c11.1 / 53436
• FlyBaseID: FBgn0040236
• Length: 1742
• Species: Drosophila melanogaster
• Sequence 2: XP_006529103.1
• Gene: Mroh2a / 100040766
• MGIID: 3705228
• Length: 1676
• Species: Mus musculus
• Alignment Length: 1709
• Identity: 336/1709 - (19%)
• Similarity: 655/1709 - (38%)
• Gaps: 335/1709 - (19%)

  Fly    37 ASTATAAPN-DKPTILEGVLHNIFDGLMDKEEQVRIAMQQAIVKILETHPERAAE-------ILS 93
            |.|.|..|. |....|..|:      :.:|.......:..|:::.|:. ||.:.:       |:.
Mouse    44 AKTDTTGPGLDMRKTLASVI------ITEKATTDPCVVMNALIRCLQM-PEISTQRKMNIYNIMQ 101

  Fly    94 EHRSQQPKMTDQTVAMLLDCIRRVVGAETPLPPAANQKLIDLALQELTKNPEHLPLIQNPAQRIL 158
            |...|:.:|.:.       ||:|:|.       .|::::.|:...|..:..|       .|...|
Mouse   102 EIIQQEGEMEEH-------CIQRLVA-------IASKQMRDITEAEDFETAE-------VASETL 145

  Fly   159 VAIGRSSPESCEQVMEALQEKGTSTEGVAHFMLMQCLGLLATENPAGVVPHIKAILSRSQPHLVG 223
            ||:.|:   ....||..||...........|::: .|..||..|....:|::...|:.....|..
Mouse   146 VALSRN---HFSLVMYELQHHLKPLNLTDEFVIV-TLAKLANGNVFEFMPYMGITLATIFTMLRL 206

  Fly   224 IRQDHIKQAHAYAIGRFSEAL------LEES--GKKEEENCSTEISVAYDVLFNQWLHSREPKVC 280
            ..:..::|....|:..|.|.:      ||:|  ....|:..:.::...|......||..::.:|.
Mouse   207 ANEAKMRQVICSAMETFCETVQFYLRHLEDSLYPVMTEDQFAVKLFPMYRYFVTVWLRHQDLEVK 271

  Fly   281 VEILQALSSMYP-LLPKDRIQDQAARLVPQILALYRRSVDRNAVTQFLCSVLKTNLALNATVLDG 344
            :.::::|..|.. |||.|.:::|....:|.:||.::..::...|||.|..:|:.::..|..:...
Mouse   272 LGVIKSLRPMLSLLLPNDDLREQVYDYIPLLLAEFQGGLEALFVTQVLRQILEASVTTNTPIPPM 336

  Fly   345 IIDVLVTHLFDLVCVYPDYEKPQTVKGHYEVLRCFHLLAGHQPYSTRIMDTLLIHLRNNSERERM 409
            ::..:.|.|...||.....::..:.:...|::.||..||  :.|...:|......:..:.|..|:
Mouse   337 LLHPIFTELHVQVCSKAPAQQQFSSQNLMEIVHCFIALA--RSYPKELMKFFFSQVEMSKEAVRV 399

  Fly   410 KSLLILTHLLNSCAGNIE-NRIPATIECLKQLILSERGIKMKLTLLKTIVALAQKSHIRDKEFVW 473
            .:|.::..::::....|. ..|...|..:|. .||:...|:::.:|:.|..|. .|..::|...|
Mouse   400 GTLALIRAVVSADDPKINIKTIYLAIRVVKN-TLSDTRSKVRMAILRIIGQLV-LSGFQEKIKGW 462

  Fly   474 ---------------FVVRHSCRFSKPSQE---HGSQEEHANLVLSCENTLYMLASTVGTLDELL 520
                           ...|..|.:.:..:|   |....:...::.|         |..|..:|..
Mouse   463 GLKYVSVQLTLSTYKLTNRRECFYQRDLEEKMVHKVTMDTVKIITS---------SISGMTNEFW 518

  Fly   521 KRELLNYLILLDYTDICGNLAKCLASLFAKSPHIEYDIAGDDAATEQATPESMGAAGEDRSVIKR 585
            .| ||.|::..|||:....:...|.:|      .|..|.|.|  ||      .|.||:.:
Mouse   519 VR-LLCYIMETDYTEALTPICISLTNL------AENQIHGKD--TE------AGIAGKSK----- 563

  Fly   586 GKVMVPGAETIYARCLALL-----GNQQCIKRCSNILSFLRYYHPQVNPALEELWERKIPDLLLQ 645
             .|.:|..:.:.||.|.|:     |..:.|.    :|:.||.....:.|::.::||::|| ||:|
Mouse   564 -HVDLPAPQKLLARLLVLMSSPYKGEGRGIA----MLNLLRTLSQSIAPSMADMWEQEIP-LLVQ 622

  Fly   646 INRE--------SAYRQLLHDFVLETNEFLGGLDENFAQRLASKLADQMYLYPMQLPHSEWHLPD 702
            ...|        ..:..:|..|:..:.:...|  .:::.||:.:|.:|:..:...
Mouse   623 YLEEHTEFTWNQKTWEDMLIQFLRNSLKKTRG--TSWSLRLSKELNNQIETFDSP---------- 675

  Fly   703 LSAERGMLLQAVALTL---LQVTDVACIHTKIDLIVTTARQERLDK-------------HVKHA- 750
             |.|:|.|.:|:..||   |:...|..:  .::|:..|......|:             .||..
Mouse   676 -SLEKGFLYRALGFTLGMGLEADRVEVL--LLELLYKTDYSNDFDREGVILCFGLCARGQVKTVL 737

  Fly   751 ----DYEKRIEPCARALGYISRQHLGHLIKKLTELAQVGGRKHSTGFFSNLHFIKDTHKELENYK 811
                |:|:||:...::.                   |:|..:            ||.....|..|
Mouse   738 NVLQDFEERIQESEQSW-------------------QIGAWR------------KDHPWRRETVK 771

  Fly   812 SNLLVVKAFGRIMDEADPLQSIQHLDEDDTLLGFLIQQLAVH------KDQTIMSAILQTLLSIC 870
            |.|:|:  :..:.....|...:.|:|..       |....:|      :|.::..|.:::::.:.
Mouse   772 SALMVM--YSCVSSYCHPQMLLTHVDSP-------ITSKIIHHYSSSCQDISLKMAFMKSVVQVT 827

  Fly   871 NQLIATKEQLPAPLRHRKQIME-TVFNIPIEAPFHDLPLLPTILKLGTDFIRIGGPDTEECVDGG 934
            |.:.:.::.......|:..:.. .|..|..|.|.|   |:..:..:..|.:
Mouse   828 NAIKSIQDPEDFQFAHKSALTGLIVVIIKAEPPDH---LVSPVRSMAMDAL-------------- 875

  Fly   935 VIFEIACRNFFGCAQQLKMK-FDSQEEDERNSFLAKHL----------NESLPQLNA-------- 980
                         :|...|| |.|.||......::.|.          |||:..|.|
Mouse   876 -------------SQLSTMKPFYSPEESTELMDISIHTVISLQPPGEDNESVKTLYANTMSSLKQ 927

  Fly   981 LVRAIVELDASPATLDLIIGILEGWTRDRNSEVRICASHVFNNTLDVYIKSMKIGCEAPSKFNQT 1045
            |:..:::....|..|...:.:||.|........|..|..:..:.:.:|::|  ||...|.|..|.
Mouse   928 LMEGLLQRQLDPKGLQDTVHLLEKWILSEKEWEREKAMALHLHLMQIYVQS--IGVCIPLKLGQF 990

  Fly  1046 GQMLGKIVPRCIDSNGTVRQVSVEILQKTLEIACIYETLTIASIDSTADWLKEIETIKEHIITDE 1110
            |.::|.|.|...|::...|..|:.:|...|::. :.:|.::......    :|::..||.:...:
Mouse   991 GVLVGLIAPCTCDAHRRTRLASINVLSSLLDLH-VSQTCSLWGTSKE----QELQKCKEDLQDTD 1050

  Fly  1111 PKQIYNLAGDIAKIIALRISSFQYLQFCKTLLHSLRDPEQSSTIGASVVLKFFIQQKGSELFHAI 1175
            ..:|.:.:..:||::....:..:.:...:.|..::...:......|...:..|:|.:..||...:
Mouse  1051 MNKISSASSRVAKVVCPEFNCDEVVSLIQKLCENIGAMDLQHDRAAVTWIGIFLQMRVKELEDKV 1115

  Fly  1176 PDLVRDSLLALRVCEVPRAKSGVLKALVALTKHHPKLVCAEMLSQPLPYDPNLVEYWHLVCNDPE 1240
            .:::...|:.|.|.:.|..:..:::.::.|..:|.:.|...:|.||||.:.:|.|.|..|..:..
Mouse  1116 AEILGAILVHLPVVDHPEVRRHLIEGILLLAHYHQETVLTSLLRQPLPMESHLTEVWLAVAENVP 1180

  Fly  1241 LTGLTLDNFLQLLSG---ASLQEGGQDASLSERQKLASGQPFAIF-----CALHEMLPCKDIKGQ 1297
            .....|...|..|..   |.:..    .|.::..:||:..|...|     |.:..::...|...:
Mouse  1181 FARTMLHGLLGRLQSRFTAKINA----TSKADIWRLAAVDPLMPFSLQTLCTIQLLMEKMDQDDK 1241

  Fly  1298 LETRFADMFCMLLTSLSSYTNLAAPNP-------INNASLSPNQTQSGKTKFGFVPNKELI--KL 1353
            ....|.|:....|..|.|.....|.:|       ::...|....|....|    :.:.:|:  ::
Mouse  1242 FPDLFPDLLYTFLLQLGSSHGPEAASPVLKTWRLVHTGPLPQEMTLQRIT----IKSMQLLVKRI 1302

  Fly  1354 N--PCQIALETFQAFLTNLE-----MEQIASVLTVNTQLASSADWHNYIELLTPMAI-GLGQQLQ 1410
            |  |.:.|||. |:..:.||     :|.::.:..:..|     :..||::.|..:.: |:|.::
Mouse  1303 NREPLEQALEE-QSVWSLLENGGTFLEGVSLMARLCMQ-----NMENYMQRLAELVLTGMGSEI- 1360

  Fly  1411 LGSPQMRQLVNSLSKYVASPYDGQRVAAVGIFSRLVPLKPTGELAASILLHL--GAALSDPNAVV 1473
                        ||..::|       .|:.:.....|:....:|...::|.|  ||. .|.:..:
Mouse  1361 ------------LSCCISS-------TAICVEFMSDPVLHQEKLLRPVVLMLEKGAG-QDKDETL 1405

  Fly  1474 RGLSIQGMGYVGQLGEKEAKRYSETAIGALLKGVDDPVGDCLINIPLESMRGLSGILRALPSERV 1538
            :.||::.:|.:.....::.|:|.:..:...|..:...|....:   .|.|..|:.:|..|....:
Mouse  1406 QVLSLRALGNMALGAPRKVKQYRKLLLEKCLGSLQGQVSSSAM---AEGMEALTKVLAELREGDI 1467

  Fly  1539 EPFHVSLAIRIRPFLGNYALEMREAAIQLFGDICE--GKHDDGSSSPTSSMEALREQLIANLFPL 1601
            .....:::.:.|.|..|.:..:|..|..|||.:.:  |         .|.....:.::......|
Mouse  1468 GSSFEAISKQCRAFFDNESELLRLKAFVLFGKLTKVVG---------ISKKHFFKGEVKRGWVSL 1523

  Fly  1602 LLHLSESEVAIASACRGTL 1620
            |||..:...::|.||..|:
Mouse  1524 LLHCQDPCPSVAQACVATM 1542

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	364	1.000	Domainoid score	I935
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	374	1.000	Inparanoid score	I2074
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43929
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3684
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.960