Protein Alignment c12.1 and CWC15

DIOPT Version :10

• Sequence 1: NP_652605.1
• Gene: c12.1 / 53435
• FlyBaseID: FBgn0040235
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_057487.2
• Gene: CWC15 / 51503
• HGNCID: 26939
• Length: 229
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 144/263 - (54%)
• Similarity: 175/263 - (66%)
• Gaps: 38/263 - (14%)

  Fly     1 MTTAARPTFDPARGGSGRGEKDLSALSKQYSSRDLPGHTKLKYRETGQGTSDENRNRDFRKELEE 65
            |||||||||:|||||.|:||.|||.|||||||||||.|||:|||:|.|...:|.||||||:||||
Human     1 MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEE 65

  Fly    66 REREARSGTGATSSSSGKALPSIVRKAIEANNAGGGSSAAKRSKPDAGQQQAQQAAQQQAANMDA 130
            |||       |.:....:..|:        ......||.:|:.:.|          |..|||:||
Human    66 RER-------AAAREKNRDRPT--------REHTTSSSVSKKPRLD----------QIPAANLDA 105

  Fly   131 DEPL-DNDSSDSDSDSDDDD-AALLAELQKIKQERLQETARRESEKKQEDERIRMENILSGNPLM 193
            |:|| |.:..|.:.:||||| |||||||:|||:||.:|.||:|.|:|.|:||||||||||||||:
Human   106 DDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLL 170

  Fly   194 NYEPGTAASAAGRASGLGGDLKIKRRWDDDVVFKNCARSAPDKK--THFVNDALRSDFHKKFMDK 256
            |....:...|         :.|:||||||||||||||:...|:|  ..||||.|||:||||||:|
Human   171 NLTGPSQPQA---------NFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEK 226

  Fly   257 YIK 259
            |||
Human   227 YIK 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
c12.1	NP_652605.1	Cwf_Cwc_15	1..258	CDD:428176	141/260 (54%)
CWC15	NP_057487.2	Cwf_Cwc_15	1..228	CDD:428176	141/260 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..133		80/156 (51%)