DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment c12.2 and stm

DIOPT Version :9

Sequence 1:	NP_001259381.1	Gene:	c12.2 / 53434	FlyBaseID:	FBgn0040234	Length:	1403	Species:	Drosophila melanogaster
Sequence 2:	NP_942112.2	Gene:	stm / 386700	ZFINID:	ZDB-GENE-031112-4	Length:	613	Species:	Danio rerio

Alignment Length:	157	Identity:	36/157 - (22%)
Similarity:	53/157 - (33%)	Gaps:	24/157 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1057 PKNEPHVGGNTWAGGSGGRDTAGLGGKGGPFRLDK--GHKVHQLSD-----EEKADVPEEIKRAA 1114
            |..|.|..||     ..|:|:.  ..|..|...||  |.......|     .||.|........|
Zfish   163 PSAEDHTDGN-----HAGKDST--DSKESPDTTDKPEGPDSDSAPDGDSASAEKTDSDHSPDEDA 220

  Fly  1115 REMNRKAFEDKLKEIKMSAHDHKLYAQFSEPNRKQVQQLKAVLEAMQTKSKERQWQKYQTHGDLD 1179
            .:.:.:|.:|...:...|..|.|..:..|:.:.|...:.:...|...:|..|   .|.|...|..
Zfish   221 NKSSTEADKDDTSDKDSSQTDEKHDSDASDKDEKHEDKDEKSDEKDSSKDSE---DKSQEKSDKS 282

  Fly  1180 DTRLVEGITGEKNIYRRRAEANPWADH 1206
            |    :|...|.:..:...|:.   ||
Zfish   283 D----DGSNSEADEQKESVESK---DH 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
c12.2	NP_001259381.1	AAA_5	112..268	CDD:285029
		AAA_5	435..595	CDD:285029
		AAA_5	770..916	CDD:285029
		vWA_F11C1-5a_type	1212..1403	CDD:238732
stm	NP_942112.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..613		36/157 (23%)
stm	NP_942112.2	PHA02664	<163..298	CDD:177447	33/148 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5271
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900